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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADAM8 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000902 cell morphogenesis ISS GO:0001525 angiogenesis ISS GO:0002523 leukocyte migration involved in inflammatory response ISS GO:0002675 positive regulation of acute inflammatory response ISS GO:0002687 positive regulation of leukocyte migration ISS GO:0002693 positive regulation of cellular extravasation IDA GO:0006508 proteolysis IEA GO:0006954 inflammatory response IDA GO:0010954 positive regulation of protein processing NAS GO:0022407 regulation of cell-cell adhesion IDA GO:0030335 positive regulation of cell migration ISS GO:0033089 positive regulation of T cell differentiation in thymus ISS GO:0035419 activation of MAPK activity involved in innate immune response ISS GO:0043524 negative regulation of neuron apoptosis ISS GO:0045780 positive regulation of bone resorption ISS GO:0045785 positive regulation of cell adhesion ISS GO:0048247 lymphocyte chemotaxis ISS GO:0050714 positive regulation of protein secretion IC GO:0051044 positive regulation of membrane protein ectodomain proteolysis IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity ISS GO:0051897 positive regulation of protein kinase B signaling cascade ISS GO:0070245 positive regulation of thymocyte apoptosis ISS GO:0071456 cellular response to hypoxia IDA GO:2000309 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production ISS cellular_component GO:0002102 podosome IDA GO:0005737 cytoplasm IDA GO:0005886 plasma membrane IDA GO:0005887 integral to plasma membrane IDA GO:0009986 cell surface IDA GO:0032010 phagolysosome IDA GO:0032127 dense core granule membrane IDA GO:0042581 specific granule IDA GO:0070820 tertiary granule IDA GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex IDA GO:0071133 alpha9-beta1 integrin-ADAM8 complex ISS molecular_function GO:0004222 metalloendopeptidase activity IEA GO:0005509 calcium ion binding ISS GO:0005515 protein binding IPI GO:0008233 peptidase activity IEA GO:0008237 metallopeptidase activity IDA GO:0008270 zinc ion binding TAS GO:0043621 protein self-association TAS GO:0050839 cell adhesion molecule binding IPI

Protein-protein interaction details for ADAM8 (Homo sapiens) (Information is obtained from BioGRID)

Not available