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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ADAM10 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001701
in utero embryonic development
IEA
GO:0001701
in utero embryonic development
ISS
GO:0006468
protein phosphorylation
IEA
GO:0006468
protein phosphorylation
ISS
GO:0006508
proteolysis
IEA
GO:0006509
membrane protein ectodomain proteolysis
IDA
GO:0006509
membrane protein ectodomain proteolysis
IMP
GO:0007162
negative regulation of cell adhesion
IDA
GO:0007162
negative regulation of cell adhesion
NAS
GO:0007173
epidermal growth factor receptor signaling pathway
TAS
GO:0007219
Notch signaling pathway
IEA
GO:0007219
Notch signaling pathway
ISS
GO:0007219
Notch signaling pathway
TAS
GO:0007220
Notch receptor processing
TAS
GO:0007229
integrin-mediated signaling pathway
IEA
GO:0007229
integrin-mediated signaling pathway
NAS
GO:0007267
cell-cell signaling
NAS
GO:0008284
positive regulation of cell proliferation
IMP
GO:0010820
positive regulation of T cell chemotaxis
IMP
GO:0030307
positive regulation of cell growth
IMP
GO:0030335
positive regulation of cell migration
IMP
GO:0034612
response to tumor necrosis factor
IDA
GO:0042117
monocyte activation
IMP
GO:0051088
PMA-inducible membrane protein ectodomain proteolysis
IMP
GO:0051089
constitutive protein ectodomain proteolysis
IDA
cellular_component
GO:0005634
nucleus
IEA
GO:0005634
nucleus
ISS
GO:0005737
cytoplasm
IEA
GO:0005737
cytoplasm
ISS
GO:0005794
Golgi apparatus
IDA
GO:0005798
Golgi-associated vesicle
IDA
GO:0005886
plasma membrane
IEA
GO:0005886
plasma membrane
TAS
GO:0009986
cell surface
IDA
GO:0012505
endomembrane system
IEA
GO:0014069
postsynaptic density
IEA
GO:0016021
integral to membrane
NAS
molecular_function
GO:0004175
endopeptidase activity
ISS
GO:0004222
metalloendopeptidase activity
IEA
GO:0004222
metalloendopeptidase activity
NAS
GO:0005102
receptor binding
NAS
GO:0005178
integrin binding
NAS
GO:0005515
protein binding
IPI
GO:0008233
peptidase activity
IEA
GO:0008237
metallopeptidase activity
IDA
GO:0008237
metallopeptidase activity
IMP
GO:0008237
metallopeptidase activity
TAS
GO:0008270
zinc ion binding
IEA
GO:0017124
SH3 domain binding
IEA
GO:0019901
protein kinase binding
IEA
GO:0019901
protein kinase binding
ISS
GO:0042803
protein homodimerization activity
IEA
GO:0042803
protein homodimerization activity
ISS
GO:0046872
metal ion binding
IEA
Protein-protein interaction details for ADAM10 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
EFNA2
Affinity Capture-Western
physical
10958785
MAD2L1
Affinity Capture-Western
physical
11741929
GRB2
Affinity Capture-Western
physical
11741929
LCK
Affinity Capture-Western
physical
11741929
UBC
Affinity Capture-MS
physical
18781797