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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for APC2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0016055 Wnt receptor signaling pathway IEA GO:0035414 negative regulation of catenin import into nucleus IDA GO:0090090 negative regulation of canonical Wnt receptor signaling pathway IDA cellular_component GO:0000139 Golgi membrane IEA GO:0005737 cytoplasm IDA GO:0005794 Golgi apparatus IDA GO:0005856 cytoskeleton IEA GO:0005881 cytoplasmic microtubule IDA GO:0005881 cytoplasmic microtubule IMP GO:0005884 actin filament IDA GO:0005886 plasma membrane IEA GO:0016342 catenin complex IDA GO:0031258 lamellipodium membrane IDA GO:0048471 perinuclear region of cytoplasm IDA molecular_function GO:0005488 binding IEA GO:0005515 protein binding IPI GO:0008013 beta-catenin binding IDA GO:0008013 beta-catenin binding IEA GO:0008017 microtubule binding IEA

Protein-protein interaction details for APC2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ACTA1 Co-localization physical 11691822 ANAPC1 Affinity Capture-Western physical 12956947 ANAPC10 Affinity Capture-Western physical 12956947 ANAPC11 Affinity Capture-Western physical 12956947 CDC27 Affinity Capture-Western physical 12956947 ANAPC4 Affinity Capture-Western physical 12956947 CDH1 Reconstituted Complex physical 12956947 CDC27 Affinity Capture-Western physical 12956947 ANAPC4 Affinity Capture-Western physical 12956947 ANAPC5 Affinity Capture-Western physical 12956947 CDC16 Affinity Capture-Western physical 12956947 ANAPC7 Affinity Capture-Western physical 12956947 CDC23 Affinity Capture-Western physical 12956947 CDC26 Affinity Capture-Western physical 12956947 CDH1 Affinity Capture-Western physical 12956947 AXIN2 Two-hybrid physical 10021369 CTNNB1 Reconstituted Complex physical 9823329 CDC27 Affinity Capture-Western physical 10922056 CTNNB1 Reconstituted Complex physical 16510875 APC2 Biochemical Activity physical 21396940 UBC Reconstituted Complex physical 21396940 CTNNB1 Two-hybrid physical 10074433