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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADORA1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000186 activation of MAPKK activity IEA GO:0001659 temperature homeostasis IEA GO:0001666 response to hypoxia IEA GO:0002087 regulation of respiratory gaseous exchange by neurological system process IEA GO:0002674 negative regulation of acute inflammatory response IEA GO:0002686 negative regulation of leukocyte migration IEA GO:0002793 positive regulation of peptide secretion IEA GO:0003093 regulation of glomerular filtration IEA GO:0006612 protein targeting to membrane IEA GO:0006909 phagocytosis TAS GO:0006954 inflammatory response TAS GO:0007165 signal transduction TAS GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway IEA GO:0007267 cell-cell signaling TAS GO:0007399 nervous system development TAS GO:0008285 negative regulation of cell proliferation IEA GO:0008624 induction of apoptosis by extracellular signals TAS GO:0014050 negative regulation of glutamate secretion IEA GO:0032229 negative regulation of synaptic transmission, GABAergic IEA GO:0032244 positive regulation of nucleoside transport IEA GO:0032900 negative regulation of neurotrophin production IEA GO:0035307 positive regulation of protein dephosphorylation IEA GO:0035814 negative regulation of renal sodium excretion IEA GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep IEA GO:0043066 negative regulation of apoptosis IEA GO:0043268 positive regulation of potassium ion transport IEA GO:0045741 positive regulation of epidermal growth factor-activated receptor activity IEA GO:0045776 negative regulation of blood pressure IEA GO:0045777 positive regulation of blood pressure IEA GO:0045822 negative regulation of heart contraction IEA GO:0045908 negative regulation of vasodilation IEA GO:0046888 negative regulation of hormone secretion IEA GO:0048167 regulation of synaptic plasticity IEA GO:0050890 cognition IEA GO:0050965 detection of temperature stimulus involved in sensory perception of pain IEA GO:0050995 negative regulation of lipid catabolic process IEA GO:0051967 negative regulation of synaptic transmission, glutamatergic IEA GO:0055118 negative regulation of cardiac muscle contraction IEA GO:0060079 regulation of excitatory postsynaptic membrane potential IEA GO:0060087 relaxation of vascular smooth muscle IEA GO:0070256 negative regulation of mucus secretion IEA cellular_component GO:0005783 endoplasmic reticulum IEA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0012505 endomembrane system IEA GO:0014069 postsynaptic density IEA GO:0016323 basolateral plasma membrane IEA GO:0030425 dendrite IEA GO:0030673 axolemma IEA GO:0032279 asymmetric synapse IEA GO:0042734 presynaptic membrane IEA GO:0043025 neuronal cell body IEA GO:0043195 terminal button IEA GO:0045211 postsynaptic membrane IEA GO:0048786 presynaptic active zone IEA molecular_function GO:0001609 adenosine receptor activity, G-protein coupled IEA GO:0001664 G-protein-coupled receptor binding IEA GO:0001883 purine nucleoside binding IEA GO:0004629 phospholipase C activity IEA GO:0004871 signal transducer activity IEA GO:0004872 receptor activity IEA GO:0005515 protein binding IPI GO:0031683 G-protein beta/gamma-subunit complex binding IEA GO:0032795 heterotrimeric G-protein binding IEA GO:0046982 protein heterodimerization activity IEA

Protein-protein interaction details for ADORA1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID DRD1 Affinity Capture-Western physical 10890919 ADA Co-localization physical 12150791 P2RY1 Affinity Capture-Western physical 11390975 GNAI2 Affinity Capture-Western physical 11369591 GRM1 Affinity Capture-Western physical 11278325