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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ADRA2A (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001819
positive regulation of cytokine production
IDA
GO:0006112
energy reserve metabolic process
TAS
GO:0006928
cellular component movement
TAS
GO:0007165
signal transduction
TAS
GO:0007186
G-protein coupled receptor protein signaling pathway
ISS
GO:0007194
negative regulation of adenylate cyclase activity
ISS
GO:0007265
Ras protein signal transduction
TAS
GO:0007266
Rho protein signal transduction
TAS
GO:0007596
blood coagulation
TAS
GO:0008284
positive regulation of cell proliferation
TAS
GO:0010700
negative regulation of norepinephrine secretion
NAS
GO:0010700
negative regulation of norepinephrine secretion
TAS
GO:0030036
actin cytoskeleton organization
TAS
GO:0030335
positive regulation of cell migration
IMP
GO:0030818
negative regulation of cAMP biosynthetic process
IDA
GO:0030818
negative regulation of cAMP biosynthetic process
ISS
GO:0032147
activation of protein kinase activity
IDA
GO:0032148
activation of protein kinase B activity
IDA
GO:0032811
negative regulation of epinephrine secretion
NAS
GO:0032870
cellular response to hormone stimulus
IGI
GO:0035625
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
IDA
GO:0042593
glucose homeostasis
IMP
GO:0042596
fear response
IEA
GO:0043268
positive regulation of potassium ion transport
ISS
GO:0043406
positive regulation of MAP kinase activity
IDA
GO:0045741
positive regulation of epidermal growth factor-activated receptor activity
IDA
GO:0045955
negative regulation of calcium ion-dependent exocytosis
IC
GO:0046676
negative regulation of insulin secretion
IMP
GO:0050796
regulation of insulin secretion
TAS
GO:0050892
intestinal absorption
TAS
GO:0050995
negative regulation of lipid catabolic process
IGI
GO:0051044
positive regulation of membrane protein ectodomain proteolysis
IDA
GO:0051927
negative regulation of calcium ion transport via voltage-gated calcium channel activity
ISS
GO:0061179
negative regulation of insulin secretion involved in cellular response to glucose stimulus
IMP
GO:0071878
negative regulation of adrenergic receptor signaling pathway
ISS
GO:0071881
inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway
IDA
GO:0071882
activation of phospholipase C activity by adrenergic receptor signaling pathway
IDA
GO:0071883
activation of MAPK activity by adrenergic receptor signaling pathway
IDA
GO:0090303
positive regulation of wound healing
IMP
cellular_component
GO:0005737
cytoplasm
IDA
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
IDA
GO:0016323
basolateral plasma membrane
TAS
GO:0043235
receptor complex
IDA
molecular_function
GO:0004871
signal transducer activity
IEA
GO:0004872
receptor activity
IEA
GO:0004930
G-protein coupled receptor activity
IEA
GO:0004935
adrenergic receptor activity
IEA
GO:0004938
alpha2-adrenergic receptor activity
IDA
GO:0004938
alpha2-adrenergic receptor activity
ISS
GO:0005515
protein binding
IPI
GO:0019901
protein kinase binding
IPI
GO:0031692
alpha-1B adrenergic receptor binding
ISS
GO:0031696
alpha-2C adrenergic receptor binding
IPI
GO:0031996
thioesterase binding
IPI
GO:0032795
heterotrimeric G-protein binding
IDA
GO:0042803
protein homodimerization activity
IDA
GO:0046982
protein heterodimerization activity
IPI
GO:0046982
protein heterodimerization activity
ISS
GO:0051379
epinephrine binding
IDA
GO:0051380
norepinephrine binding
IDA
Protein-protein interaction details for ADRA2A (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
PPP1R9B
Reconstituted Complex
physical
11154706