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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ADRA2A (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001819positive regulation of cytokine productionIDA
GO:0006112energy reserve metabolic processTAS
GO:0006928cellular component movementTAS
GO:0007165signal transductionTAS
GO:0007186G-protein coupled receptor protein signaling pathwayISS
GO:0007194negative regulation of adenylate cyclase activityISS
GO:0007265Ras protein signal transductionTAS
GO:0007266Rho protein signal transductionTAS
GO:0007596blood coagulationTAS
GO:0008284positive regulation of cell proliferationTAS
GO:0010700negative regulation of norepinephrine secretionNAS
GO:0010700negative regulation of norepinephrine secretionTAS
GO:0030036actin cytoskeleton organizationTAS
GO:0030335positive regulation of cell migrationIMP
GO:0030818negative regulation of cAMP biosynthetic processIDA
GO:0030818negative regulation of cAMP biosynthetic processISS
GO:0032147activation of protein kinase activityIDA
GO:0032148activation of protein kinase B activityIDA
GO:0032811negative regulation of epinephrine secretionNAS
GO:0032870cellular response to hormone stimulusIGI
GO:0035625epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayIDA
GO:0042593glucose homeostasisIMP
GO:0042596fear responseIEA
GO:0043268positive regulation of potassium ion transportISS
GO:0043406positive regulation of MAP kinase activityIDA
GO:0045741positive regulation of epidermal growth factor-activated receptor activityIDA
GO:0045955negative regulation of calcium ion-dependent exocytosisIC
GO:0046676negative regulation of insulin secretionIMP
GO:0050796regulation of insulin secretionTAS
GO:0050892intestinal absorptionTAS
GO:0050995negative regulation of lipid catabolic processIGI
GO:0051044positive regulation of membrane protein ectodomain proteolysisIDA
GO:0051927negative regulation of calcium ion transport via voltage-gated calcium channel activityISS
GO:0061179negative regulation of insulin secretion involved in cellular response to glucose stimulusIMP
GO:0071878negative regulation of adrenergic receptor signaling pathwayISS
GO:0071881inhibition of adenylate cyclase activity by adrenergic receptor signaling pathwayIDA
GO:0071882activation of phospholipase C activity by adrenergic receptor signaling pathwayIDA
GO:0071883activation of MAPK activity by adrenergic receptor signaling pathwayIDA
GO:0090303positive regulation of wound healingIMP
cellular_component
GO:0005737cytoplasmIDA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIDA
GO:0016323basolateral plasma membraneTAS
GO:0043235receptor complexIDA
molecular_function
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIEA
GO:0004935adrenergic receptor activityIEA
GO:0004938alpha2-adrenergic receptor activityIDA
GO:0004938alpha2-adrenergic receptor activityISS
GO:0005515protein bindingIPI
GO:0019901protein kinase bindingIPI
GO:0031692alpha-1B adrenergic receptor bindingISS
GO:0031696alpha-2C adrenergic receptor bindingIPI
GO:0031996thioesterase bindingIPI
GO:0032795heterotrimeric G-protein bindingIDA
GO:0042803protein homodimerization activityIDA
GO:0046982protein heterodimerization activityIPI
GO:0046982protein heterodimerization activityISS
GO:0051379epinephrine bindingIDA
GO:0051380norepinephrine bindingIDA

Protein-protein interaction details for ADRA2A (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PPP1R9BReconstituted Complexphysical11154706