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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for AGTR1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001558
regulation of cell growth
NAS
GO:0001822
kidney development
IMP
GO:0002018
renin-angiotensin regulation of aldosterone production
NAS
GO:0002034
regulation of blood vessel size by renin-angiotensin
IC
GO:0003081
regulation of systemic arterial blood pressure by renin-angiotensin
IC
GO:0007186
G-protein coupled receptor protein signaling pathway
IDA
GO:0007200
activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
NAS
GO:0007204
elevation of cytosolic calcium ion concentration
IDA
GO:0007266
Rho protein signal transduction
IDA
GO:0010744
positive regulation of macrophage derived foam cell differentiation
IC
GO:0010873
positive regulation of cholesterol esterification
IMP
GO:0019229
regulation of vasoconstriction
IC
GO:0019229
regulation of vasoconstriction
IDA
GO:0019229
regulation of vasoconstriction
NAS
GO:0019722
calcium-mediated signaling
IDA
GO:0032270
positive regulation of cellular protein metabolic process
IMP
GO:0032430
positive regulation of phospholipase A2 activity
IMP
GO:0033864
positive regulation of NAD(P)H oxidase activity
TAS
GO:0034374
low-density lipoprotein particle remodeling
NAS
GO:0035813
regulation of renal sodium excretion
NAS
GO:0042127
regulation of cell proliferation
NAS
GO:0042312
regulation of vasodilation
IC
GO:0050727
regulation of inflammatory response
IC
GO:0050729
positive regulation of inflammatory response
TAS
GO:0051482
elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger
IDA
GO:0060326
cell chemotaxis
IDA
GO:2000379
positive regulation of reactive oxygen species metabolic process
TAS
cellular_component
GO:0005886
plasma membrane
IDA
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
IC
GO:0016021
integral to membrane
NAS
molecular_function
GO:0001596
angiotensin type I receptor activity
IDA
GO:0001596
angiotensin type I receptor activity
IPI
GO:0004871
signal transducer activity
IEA
GO:0004872
receptor activity
IEA
GO:0004930
G-protein coupled receptor activity
IEA
GO:0004945
angiotensin type II receptor activity
IDA
GO:0005515
protein binding
IPI
GO:0010698
acetyltransferase activator activity
IMP
GO:0031711
bradykinin receptor binding
IPI
GO:0046982
protein heterodimerization activity
IPI
Protein-protein interaction details for AGTR1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
ZBTB16
Two-hybrid
physical
14657020
ZBTB16
Reconstituted Complex
physical
14657020
ADRBK1
Affinity Capture-Western
physical
9211925
GRK5
Affinity Capture-Western
physical
9211925
RAB5A
Reconstituted Complex
physical
11682489
BDKRB2
Co-fractionation
physical
10993080
AGTRAP
Reconstituted Complex
physical
11733189
TRAF3
Affinity Capture-Western
physical
11226259
MAPK1
Affinity Capture-Western
physical
11226259
ARRB2
Affinity Capture-Western
physical
11226259