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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AGTR1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001558regulation of cell growthNAS
GO:0001822kidney developmentIMP
GO:0002018renin-angiotensin regulation of aldosterone productionNAS
GO:0002034regulation of blood vessel size by renin-angiotensinIC
GO:0003081regulation of systemic arterial blood pressure by renin-angiotensinIC
GO:0007186G-protein coupled receptor protein signaling pathwayIDA
GO:0007200activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messengerNAS
GO:0007204elevation of cytosolic calcium ion concentrationIDA
GO:0007266Rho protein signal transductionIDA
GO:0010744positive regulation of macrophage derived foam cell differentiationIC
GO:0010873positive regulation of cholesterol esterificationIMP
GO:0019229regulation of vasoconstrictionIC
GO:0019229regulation of vasoconstrictionIDA
GO:0019229regulation of vasoconstrictionNAS
GO:0019722calcium-mediated signalingIDA
GO:0032270positive regulation of cellular protein metabolic processIMP
GO:0032430positive regulation of phospholipase A2 activityIMP
GO:0033864positive regulation of NAD(P)H oxidase activityTAS
GO:0034374low-density lipoprotein particle remodelingNAS
GO:0035813regulation of renal sodium excretionNAS
GO:0042127regulation of cell proliferationNAS
GO:0042312regulation of vasodilationIC
GO:0050727regulation of inflammatory responseIC
GO:0050729positive regulation of inflammatory responseTAS
GO:0051482elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messengerIDA
GO:0060326cell chemotaxisIDA
GO:2000379positive regulation of reactive oxygen species metabolic processTAS
cellular_component
GO:0005886plasma membraneIDA
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIC
GO:0016021integral to membraneNAS
molecular_function
GO:0001596angiotensin type I receptor activityIDA
GO:0001596angiotensin type I receptor activityIPI
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIEA
GO:0004945angiotensin type II receptor activityIDA
GO:0005515protein bindingIPI
GO:0010698acetyltransferase activator activityIMP
GO:0031711bradykinin receptor bindingIPI
GO:0046982protein heterodimerization activityIPI

Protein-protein interaction details for AGTR1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ZBTB16Two-hybridphysical14657020
ZBTB16Reconstituted Complexphysical14657020
ADRBK1Affinity Capture-Westernphysical9211925
GRK5Affinity Capture-Westernphysical9211925
RAB5AReconstituted Complexphysical11682489
BDKRB2Co-fractionationphysical10993080
AGTRAPReconstituted Complexphysical11733189
TRAF3Affinity Capture-Westernphysical11226259
MAPK1Affinity Capture-Westernphysical11226259
ARRB2Affinity Capture-Westernphysical11226259