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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for AGTR2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001974
blood vessel remodeling
TAS
GO:0001991
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
ISS
GO:0002033
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
IEA
GO:0002035
brain renin-angiotensin system
IEA
GO:0007166
cell surface receptor linked signaling pathway
IDA
GO:0007186
G-protein coupled receptor protein signaling pathway
IC
GO:0007199
G-protein signaling, coupled to cGMP nucleotide second messenger
ISS
GO:0007243
intracellular protein kinase cascade
ISS
GO:0007263
nitric oxide mediated signal transduction
IC
GO:0007263
nitric oxide mediated signal transduction
TAS
GO:0007420
brain development
NAS
GO:0007610
behavior
IMP
GO:0007610
behavior
ISS
GO:0008217
regulation of blood pressure
TAS
GO:0009968
negative regulation of signal transduction
TAS
GO:0010459
negative regulation of heart rate
ISS
GO:0030308
negative regulation of cell growth
TAS
GO:0032516
positive regulation of phosphoprotein phosphatase activity
IDA
GO:0035566
regulation of metanephros size
IEA
GO:0043065
positive regulation of apoptosis
IMP
GO:0043537
negative regulation of blood vessel endothelial cell migration
NAS
GO:0045429
positive regulation of nitric oxide biosynthetic process
IC
GO:0045893
positive regulation of transcription, DNA-dependent
IEA
GO:0045909
positive regulation of vasodilation
IDA
GO:0051000
positive regulation of nitric-oxide synthase activity
ISS
GO:0051387
negative regulation of nerve growth factor receptor signaling pathway
IMP
GO:0072300
positive regulation of metanephric glomerulus development
IEA
GO:0090190
positive regulation of branching involved in ureteric bud morphogenesis
IEA
cellular_component
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
IC
molecular_function
GO:0004871
signal transducer activity
IEA
GO:0004872
receptor activity
IEA
GO:0004930
G-protein coupled receptor activity
IEA
GO:0004945
angiotensin type II receptor activity
IPI
GO:0005515
protein binding
IPI
GO:0048019
receptor antagonist activity
TAS
Protein-protein interaction details for AGTR2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
MTUS1
Two-hybrid
physical
15123706
MTUS1
Affinity Capture-Western
physical
15123706
AGTRAP
Reconstituted Complex
physical
11733189