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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AGTR2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001974blood vessel remodelingTAS
GO:0001991regulation of systemic arterial blood pressure by circulatory renin-angiotensinISS
GO:0002033vasodilation by angiotensin involved in regulation of systemic arterial blood pressureIEA
GO:0002035brain renin-angiotensin systemIEA
GO:0007166cell surface receptor linked signaling pathwayIDA
GO:0007186G-protein coupled receptor protein signaling pathwayIC
GO:0007199G-protein signaling, coupled to cGMP nucleotide second messengerISS
GO:0007243intracellular protein kinase cascadeISS
GO:0007263nitric oxide mediated signal transductionIC
GO:0007263nitric oxide mediated signal transductionTAS
GO:0007420brain developmentNAS
GO:0007610behaviorIMP
GO:0007610behaviorISS
GO:0008217regulation of blood pressureTAS
GO:0009968negative regulation of signal transductionTAS
GO:0010459negative regulation of heart rateISS
GO:0030308negative regulation of cell growthTAS
GO:0032516positive regulation of phosphoprotein phosphatase activityIDA
GO:0035566regulation of metanephros sizeIEA
GO:0043065positive regulation of apoptosisIMP
GO:0043537negative regulation of blood vessel endothelial cell migrationNAS
GO:0045429positive regulation of nitric oxide biosynthetic processIC
GO:0045893positive regulation of transcription, DNA-dependentIEA
GO:0045909positive regulation of vasodilationIDA
GO:0051000positive regulation of nitric-oxide synthase activityISS
GO:0051387negative regulation of nerve growth factor receptor signaling pathwayIMP
GO:0072300positive regulation of metanephric glomerulus developmentIEA
GO:0090190positive regulation of branching involved in ureteric bud morphogenesisIEA
cellular_component
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIC
molecular_function
GO:0004871signal transducer activityIEA
GO:0004872receptor activityIEA
GO:0004930G-protein coupled receptor activityIEA
GO:0004945angiotensin type II receptor activityIPI
GO:0005515protein bindingIPI
GO:0048019receptor antagonist activityTAS

Protein-protein interaction details for AGTR2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
MTUS1Two-hybridphysical15123706
MTUS1Affinity Capture-Westernphysical15123706
AGTRAPReconstituted Complexphysical11733189