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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ABCA1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002790
peptide secretion
IEA
GO:0006497
protein lipidation
IEA
GO:0006629
lipid metabolic process
TAS
GO:0006810
transport
IEA
GO:0006820
anion transport
ISS
GO:0006911
phagocytosis, engulfment
IEA
GO:0007040
lysosome organization
IDA
GO:0007186
G-protein coupled receptor protein signaling pathway
IMP
GO:0008202
steroid metabolic process
IEA
GO:0008203
cholesterol metabolic process
IDA
GO:0010745
negative regulation of macrophage derived foam cell differentiation
TAS
GO:0010875
positive regulation of cholesterol efflux
IEA
GO:0010887
negative regulation of cholesterol storage
TAS
GO:0016197
endosome transport
IDA
GO:0030819
positive regulation of cAMP biosynthetic process
IMP
GO:0032367
intracellular cholesterol transport
IMP
GO:0032488
Cdc42 protein signal transduction
IMP
GO:0033344
cholesterol efflux
IDA
GO:0033344
cholesterol efflux
IMP
GO:0033700
phospholipid efflux
IDA
GO:0033700
phospholipid efflux
IMP
GO:0034380
high-density lipoprotein particle assembly
IMP
GO:0038027
apolipoprotein A-I-mediated signaling pathway
IDA
GO:0042157
lipoprotein metabolic process
TAS
GO:0042632
cholesterol homeostasis
IDA
GO:0043691
reverse cholesterol transport
IMP
GO:0044255
cellular lipid metabolic process
TAS
GO:0045332
phospholipid translocation
IEA
GO:0050702
interleukin-1 beta secretion
IMP
GO:0055091
phospholipid homeostasis
IMP
GO:0060155
platelet dense granule organization
IMP
GO:0071222
cellular response to lipopolysaccharide
IEA
GO:0071300
cellular response to retinoic acid
IEA
cellular_component
GO:0005622
intracellular
IMP
GO:0005624
membrane fraction
IDA
GO:0005794
Golgi apparatus
IEA
GO:0005886
plasma membrane
TAS
GO:0005887
integral to plasma membrane
IDA
GO:0030139
endocytic vesicle
IDA
GO:0045121
membrane raft
IDA
GO:0045335
phagocytic vesicle
IDA
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0005515
protein binding
IPI
GO:0005524
ATP binding
IDA
GO:0005524
ATP binding
IEA
GO:0005543
phospholipid binding
IC
GO:0005548
phospholipid transporter activity
IDA
GO:0008509
anion transmembrane transporter activity
ISS
GO:0015485
cholesterol binding
IC
GO:0016887
ATPase activity
IEA
GO:0017127
cholesterol transporter activity
IDA
GO:0030349
syntaxin-13 binding
IPI
GO:0031267
small GTPase binding
IPI
GO:0034185
apolipoprotein binding
IPI
GO:0034186
apolipoprotein A-I binding
IPI
GO:0034188
apolipoprotein A-I receptor activity
IDA
Protein-protein interaction details for ABCA1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
FADD
Two-hybrid
physical
12235128
CREBBP
Affinity Capture-Western
physical
11864601
FADD
Reconstituted Complex
physical
12235128
FADD
Reconstituted Complex
physical
12235128
APOA1
Reconstituted Complex
physical
12084722
APOA1
Reconstituted Complex
physical
12084722
XPC
Reconstituted Complex
physical
12505994
XPC
Two-hybrid
physical
12505994
XPC
Two-hybrid
physical
12505994
SNTB2
Two-hybrid
physical
12054535
UGP1
Two-hybrid
physical
12054535
SDHB
Two-hybrid
physical
12054535
AOX1
Two-hybrid
physical
12054535
PRPF8
Two-hybrid
physical
12054535
SNTB2
Affinity Capture-Western
physical
12054535
UBC
Affinity Capture-Western
physical
21520210
HGS
Affinity Capture-Western
physical
21520210
COPS5
Affinity Capture-Western
physical
19268428
COPS5
Affinity Capture-Western
physical
19268428
COPS2
Affinity Capture-Western
physical
19268428
UBC
Affinity Capture-Western
physical
19268428
CSNK2A2
Biochemical Activity
physical
15218032
UBC
Affinity Capture-Western
physical
21817095