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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARHGEF12 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006915 apoptosis TAS GO:0007186 G-protein coupled receptor protein signaling pathway IDA GO:0007264 small GTPase mediated signal transduction TAS GO:0007411 axon guidance TAS GO:0008624 induction of apoptosis by extracellular signals TAS GO:0035023 regulation of Rho protein signal transduction IEA GO:0035556 intracellular signal transduction IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051056 regulation of small GTPase mediated signal transduction TAS cellular_component GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0016020 membrane IEA molecular_function GO:0001664 G-protein-coupled receptor binding IDA GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005096 GTPase activator activity IEA

Protein-protein interaction details for ARHGEF12 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ARHGEF12 Affinity Capture-Western physical 14712228 RHOA Reconstituted Complex physical 11373293 IGF1R Two-hybrid physical 11724822 IGF1R Reconstituted Complex physical 11724822 IGF1R Affinity Capture-Western physical 11724822 PLXNB2 Affinity Capture-Western physical 12183458 PLXNB1 Affinity Capture-Western physical 12220504 PLXNB1 Two-hybrid physical 12220504 GNA12 Affinity Capture-Western physical 11094164 GNA13 Affinity Capture-Western physical 11094164 GNA12 Phenotypic Enhancement genetic 12515866 GNA13 Phenotypic Enhancement genetic 12515866 TEC Phenotypic Enhancement genetic 12515866 TEC Biochemical Activity physical 12515866 RHOA Reconstituted Complex physical 12515866 CUL3 Two-hybrid physical 21670212 CUL3 Affinity Capture-Western physical 21670212 CUL3 Reconstituted Complex physical 21670212 CUL3 Biochemical Activity physical 21670212