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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ALOX12 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006916 anti-apoptosis IMP GO:0006916 anti-apoptosis ISS GO:0006928 cellular component movement IMP GO:0008284 positive regulation of cell proliferation IMP GO:0008284 positive regulation of cell proliferation ISS GO:0010595 positive regulation of endothelial cell migration IEA GO:0010628 positive regulation of gene expression IEA GO:0019370 leukotriene biosynthetic process IEA GO:0019395 fatty acid oxidation IMP GO:0030307 positive regulation of cell growth IMP GO:0031342 negative regulation of cell killing IEA GO:0031343 positive regulation of cell killing IEA GO:0042554 superoxide anion generation NAS GO:0043065 positive regulation of apoptosis IEA GO:0043280 positive regulation of caspase activity IEA GO:0045603 positive regulation of endothelial cell differentiation IEA GO:0045785 positive regulation of cell adhesion IMP GO:0051901 positive regulation of mitochondrial depolarization IEA GO:0072593 reactive oxygen species metabolic process NAS cellular_component GO:0005737 cytoplasm IEA GO:0005829 cytosol IDA GO:0042383 sarcolemma IDA molecular_function GO:0004052 arachidonate 12-lipoxygenase activity IDA GO:0005506 iron ion binding IEA GO:0005515 protein binding IPI GO:0016165 lipoxygenase activity IEA GO:0016491 oxidoreductase activity IEA GO:0046872 metal ion binding IEA GO:0047977 hepoxilin-epoxide hydrolase activity ISS

Protein-protein interaction details for ALOX12 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID LMNA Two-hybrid physical 10727209 ITGB4 Two-hybrid physical 10727209 TRIB1 Two-hybrid physical 10727209 KRT5 Two-hybrid physical 10727209 LMNA Affinity Capture-Western physical 10727209 KRT5 Affinity Capture-Western physical 10727209