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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ALOX5 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002526
acute inflammatory response
IEA
GO:0002540
leukotriene production involved in inflammatory response
IEA
GO:0006691
leukotriene metabolic process
IEA
GO:0006691
leukotriene metabolic process
TAS
GO:0006692
prostanoid metabolic process
TAS
GO:0007584
response to nutrient
IEA
GO:0019233
sensory perception of pain
IEA
GO:0019369
arachidonic acid metabolic process
IEA
GO:0019370
leukotriene biosynthetic process
IDA
GO:0019370
leukotriene biosynthetic process
TAS
GO:0019372
lipoxygenase pathway
IEA
GO:0045907
positive regulation of vasoconstriction
IEA
GO:0055093
response to hyperoxia
IEA
cellular_component
GO:0005625
soluble fraction
IEA
GO:0005634
nucleus
IEA
GO:0005635
nuclear envelope
IDA
GO:0005641
nuclear envelope lumen
IDA
GO:0005737
cytoplasm
IEA
GO:0005829
cytosol
IDA
GO:0005829
cytosol
TAS
GO:0016020
membrane
IEA
GO:0016363
nuclear matrix
IDA
GO:0030425
dendrite
IEA
GO:0031965
nuclear membrane
IDA
GO:0042383
sarcolemma
IEA
molecular_function
GO:0004051
arachidonate 5-lipoxygenase activity
IDA
GO:0004051
arachidonate 5-lipoxygenase activity
IEA
GO:0004051
arachidonate 5-lipoxygenase activity
TAS
GO:0005506
iron ion binding
IDA
GO:0005506
iron ion binding
IEA
GO:0005515
protein binding
IPI
GO:0016165
lipoxygenase activity
IEA
GO:0016491
oxidoreductase activity
IEA
GO:0046872
metal ion binding
IEA
Protein-protein interaction details for ALOX5 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
COTL1
Two-hybrid
physical
11297527
TGFBRAP1
Two-hybrid
physical
10051563
COTL1P1
Two-hybrid
physical
10051563
GRB2
Reconstituted Complex
physical
8585605
GRB2
Reconstituted Complex
physical
7929073
COTL1
Reconstituted Complex
physical
11297527
COTL1
Affinity Capture-Western
physical
11297527