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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ANAPC2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000079 regulation of cyclin-dependent protein kinase activity TAS GO:0000278 mitotic cell cycle TAS GO:0006511 ubiquitin-dependent protein catabolic process IEA GO:0007067 mitosis IEA GO:0007094 mitotic cell cycle spindle assembly checkpoint TAS GO:0007399 nervous system development IEA GO:0008054 cyclin catabolic process TAS GO:0016567 protein ubiquitination TAS GO:0030154 cell differentiation IEA GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0031915 positive regulation of synaptic plasticity ISS GO:0045773 positive regulation of axon extension IEA GO:0050775 positive regulation of dendrite morphogenesis IEA GO:0051301 cell division IEA GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0070979 protein K11-linked ubiquitination IDA GO:0090129 positive regulation of synapse maturation ISS cellular_component GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005680 anaphase-promoting complex IDA GO:0005829 cytosol TAS molecular_function GO:0004842 ubiquitin-protein ligase activity TAS GO:0031625 ubiquitin protein ligase binding IEA

Protein-protein interaction details for ANAPC2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ANAPC1 Reconstituted Complex physical 12956947 ANAPC4 Reconstituted Complex physical 12956947 ANAPC5 Reconstituted Complex physical 12956947 ANAPC11 Reconstituted Complex physical 11739784 ANAPC11 Reconstituted Complex physical 11739784 UBE2C Reconstituted Complex physical 11739784 ANAPC1 Co-purification physical 11076961 ANAPC11 Two-hybrid physical 10230407 UBE2C Co-fractionation physical 17443186 EP300 Affinity Capture-Western physical 16319895 CREBBP Affinity Capture-Western physical 16319895 FZR1 Affinity Capture-Western physical 16287863 CDC20 Affinity Capture-Western physical 16287863 CDC27 Affinity Capture-MS physical 14657031 KIAA0174 Affinity Capture-Western physical 21439932 PTTG1 Biochemical Activity physical 20080579 CCNB1 Biochemical Activity physical 20080579 UFD1L Two-hybrid physical 21900206 CDC27 Affinity Capture-MS physical 22193957 CCNB1 Biochemical Activity physical 22193957 PTTG1 Biochemical Activity physical 22193957 CDC20 Affinity Capture-Western physical 22193957 BUB1B Affinity Capture-Western physical 22193957 MAD2L1 Affinity Capture-Western physical 22193957 CCNB1 Affinity Capture-Western physical 22193957 UBC Affinity Capture-MS physical 21987572