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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for AIRE (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006355 regulation of transcription, DNA-dependent IDA GO:0006955 immune response TAS GO:0006959 humoral immune response IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA cellular_component GO:0005634 nucleus NAS GO:0005737 cytoplasm IEA molecular_function GO:0003677 DNA binding IEA GO:0003682 chromatin binding IDA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IDA GO:0008270 zinc ion binding IEA GO:0042393 histone binding IDA GO:0044212 transcription regulatory region DNA binding IDA GO:0045182 translation regulator activity IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for AIRE (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CREBBP Two-hybrid physical 10748110 AIRE Two-hybrid physical 10748110 AIRE Reconstituted Complex physical 10748110 CREBBP Far Western physical 10748110 AIRE Reconstituted Complex physical 12929931 AIRE Two-hybrid physical 12929931 CREBBP Far Western physical 12929931 CREBBP Two-hybrid physical 12929931 MYBBP1A Affinity Capture-MS physical 20085707 NOP56 Affinity Capture-MS physical 20085707 DDX5 Affinity Capture-MS physical 20085707 DDX17 Affinity Capture-MS physical 20085707 RUVBL2 Affinity Capture-MS physical 20085707 TOP2A Affinity Capture-MS physical 20085707 PRKDC Affinity Capture-MS physical 20085707 SSRP1 Affinity Capture-MS physical 20085707 PARP1 Affinity Capture-MS physical 20085707 POLR2A Affinity Capture-MS physical 20085707 PCNA Affinity Capture-MS physical 20085707 POLR2B Affinity Capture-MS physical 20085707 MCM2 Affinity Capture-MS physical 20085707 MCM5 Affinity Capture-MS physical 20085707 MCM6 Affinity Capture-MS physical 20085707 MSH6 Affinity Capture-MS physical 20085707 HIST1H2AC Affinity Capture-MS physical 20085707 HIST1H2BO Affinity Capture-MS physical 20085707 MSH2 Affinity Capture-MS physical 20085707 NASP Affinity Capture-MS physical 20085707 RAD21 Affinity Capture-MS physical 20085707 SMC1A Affinity Capture-MS physical 20085707 SMC3 Affinity Capture-MS physical 20085707 CHD6 Affinity Capture-MS physical 20085707 TRIM28 Affinity Capture-MS physical 20085707 LMNB1 Affinity Capture-MS physical 20085707 KPNB1 Affinity Capture-MS physical 20085707 XPO1 Affinity Capture-MS physical 20085707 IPO7 Affinity Capture-MS physical 20085707 XPOT Affinity Capture-MS physical 20085707 RANBP2 Affinity Capture-MS physical 20085707 RANBP9 Affinity Capture-MS physical 20085707 NUP93 Affinity Capture-MS physical 20085707 SRSF3 Affinity Capture-MS physical 20085707 SRSF1 Affinity Capture-MS physical 20085707 PABPC1 Affinity Capture-MS physical 20085707 SRSF2 Affinity Capture-MS physical 20085707 SNRPD3 Affinity Capture-MS physical 20085707 EFTUD2 Affinity Capture-MS physical 20085707 SNRPB Affinity Capture-MS physical 20085707 GEMIN5 Affinity Capture-MS physical 20085707 PRKDC Affinity Capture-Western physical 20085707 SSRP1 Affinity Capture-Western physical 20085707 TOP2A Affinity Capture-Western physical 20085707 LMNB1 Affinity Capture-Western physical 20085707 NUP93 Affinity Capture-Western physical 20085707 NASP Affinity Capture-Western physical 20085707 DDX5 Affinity Capture-Western physical 20085707 SRSF2 Affinity Capture-Western physical 20085707 MYBBP1A Affinity Capture-Western physical 20085707 TRIM28 Affinity Capture-Western physical 20085707 RAD21 Affinity Capture-Western physical 20085707 SMC1A Affinity Capture-Western physical 20085707 HSPA5 Affinity Capture-MS physical 15150263 HSPA4 Affinity Capture-MS physical 15150263 HIST1H3A Reconstituted Complex physical 18292755 HIST2H2BE Reconstituted Complex physical 18292755 HIST1H3A Protein-peptide physical 18292755 HIST1H3A Affinity Capture-Western physical 18292755 HIST1H3A Co-crystal Structure physical 18292755