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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for APOA1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001932 regulation of protein phosphorylation IEA GO:0001935 endothelial cell proliferation IEA GO:0002576 platelet degranulation TAS GO:0002740 negative regulation of cytokine secretion involved in immune response IDA GO:0006629 lipid metabolic process TAS GO:0006644 phospholipid metabolic process IEA GO:0006656 phosphatidylcholine biosynthetic process IDA GO:0006695 cholesterol biosynthetic process IEA GO:0006869 lipid transport IEA GO:0007186 G-protein coupled receptor protein signaling pathway IDA GO:0007596 blood coagulation TAS GO:0008202 steroid metabolic process IEA GO:0008203 cholesterol metabolic process IMP GO:0008211 glucocorticoid metabolic process IEA GO:0010873 positive regulation of cholesterol esterification IDA GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling IDA GO:0019915 lipid storage IEA GO:0030168 platelet activation TAS GO:0030300 regulation of intestinal cholesterol absorption IEA GO:0030301 cholesterol transport IDA GO:0030325 adrenal gland development IEA GO:0032488 Cdc42 protein signal transduction IDA GO:0033344 cholesterol efflux IDA GO:0033700 phospholipid efflux IDA GO:0034375 high-density lipoprotein particle remodeling IC GO:0034380 high-density lipoprotein particle assembly IDA GO:0034384 high-density lipoprotein particle clearance IC GO:0042157 lipoprotein metabolic process IEA GO:0042157 lipoprotein metabolic process TAS GO:0042158 lipoprotein biosynthetic process IEA GO:0042632 cholesterol homeostasis IMP GO:0043534 blood vessel endothelial cell migration IEA GO:0043691 reverse cholesterol transport IMP GO:0044255 cellular lipid metabolic process TAS GO:0050713 negative regulation of interleukin-1 beta secretion IDA GO:0050821 protein stabilization IDA GO:0051345 positive regulation of hydrolase activity IDA GO:0051346 negative regulation of hydrolase activity IEA GO:0051347 positive regulation of transferase activity IEA GO:0055085 transmembrane transport TAS GO:0070508 cholesterol import IMP cellular_component GO:0005576 extracellular region IEA GO:0005576 extracellular region TAS GO:0005615 extracellular space IDA GO:0005788 endoplasmic reticulum lumen TAS GO:0005886 plasma membrane TAS GO:0030139 endocytic vesicle IDA GO:0030141 stored secretory granule TAS GO:0031410 cytoplasmic vesicle IDA GO:0034361 very-low-density lipoprotein particle IDA GO:0034364 high-density lipoprotein particle IDA GO:0034366 spherical high-density lipoprotein particle IDA molecular_function GO:0001540 beta-amyloid binding IDA GO:0005319 lipid transporter activity IEA GO:0005515 protein binding IPI GO:0005543 phospholipid binding IDA GO:0008035 high-density lipoprotein particle binding IEA GO:0008289 lipid binding IEA GO:0015485 cholesterol binding IDA GO:0017127 cholesterol transporter activity IDA GO:0017127 cholesterol transporter activity IMP GO:0019899 enzyme binding IPI GO:0034190 apolipoprotein receptor binding IPI GO:0034191 apolipoprotein A-I receptor binding IPI GO:0042802 identical protein binding IPI GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity IDA GO:0070653 high-density lipoprotein particle receptor binding IPI

Protein-protein interaction details for APOA1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PDE1A Two-hybrid physical 11991719 MAP7D1 Two-hybrid physical 16169070 TNFRSF10C Two-hybrid physical 16169070 TOMM20 Two-hybrid physical 16169070 APOL1 Co-purification physical 9325276 APOF Co-purification physical 6816269 PLTP Reconstituted Complex physical 9469594 PLTP Co-purification physical 9469594 ABCA1 Reconstituted Complex physical 12084722 ABCA1 Reconstituted Complex physical 12084722 GPLD1 Affinity Capture-Western physical 11254757 GPLD1 Reconstituted Complex physical 11254757 LBP Affinity Capture-Western physical 8663389 APOA1 Co-crystal Structure physical 9356442 LCAT Reconstituted Complex physical 1644835 CD40LG Affinity Capture-Western physical 10085035 APOC1 Two-hybrid physical 11991719 SAA2 Two-hybrid physical 11991719 APOA1BP Affinity Capture-Western physical 11991719 UCHL5 Affinity Capture-MS physical 21800051 MIS12 Affinity Capture-MS physical 20360068 CLEC4G Two-hybrid physical 18624398 MAPK6 Two-hybrid physical 21900206