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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for APOB (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001701 in utero embryonic development IEA GO:0006629 lipid metabolic process TAS GO:0006642 triglyceride mobilization IEA GO:0006810 transport IEA GO:0006898 receptor-mediated endocytosis TAS GO:0007283 spermatogenesis IEA GO:0007399 nervous system development IEA GO:0007596 blood coagulation TAS GO:0008202 steroid metabolic process IEA GO:0008203 cholesterol metabolic process IMP GO:0009566 fertilization IEA GO:0009615 response to virus IEP GO:0009743 response to carbohydrate stimulus IEA GO:0009791 post-embryonic development IEA GO:0010269 response to selenium ion IEA GO:0010744 positive regulation of macrophage derived foam cell differentiation IDA GO:0010884 positive regulation of lipid storage IDA GO:0010886 positive regulation of cholesterol storage IDA GO:0016042 lipid catabolic process IEA GO:0019433 triglyceride catabolic process IEA GO:0030168 platelet activation TAS GO:0030301 cholesterol transport IMP GO:0030317 sperm motility IEA GO:0032496 response to lipopolysaccharide IEA GO:0034374 low-density lipoprotein particle remodeling IMP GO:0034379 very-low-density lipoprotein particle assembly IC GO:0034383 low-density lipoprotein particle clearance IMP GO:0042157 lipoprotein metabolic process TAS GO:0042158 lipoprotein biosynthetic process IEA GO:0042159 lipoprotein catabolic process IEA GO:0042632 cholesterol homeostasis IMP GO:0042953 lipoprotein transport IEA GO:0045540 regulation of cholesterol biosynthetic process IEA GO:0048844 artery morphogenesis IEA GO:0050900 leukocyte migration TAS GO:0071356 cellular response to tumor necrosis factor IEA GO:0071379 cellular response to prostaglandin stimulus IEA cellular_component GO:0005576 extracellular region TAS GO:0005615 extracellular space IEA GO:0005783 endoplasmic reticulum IEA GO:0005788 endoplasmic reticulum lumen TAS GO:0005789 endoplasmic reticulum membrane TAS GO:0005792 microsome IEA GO:0005886 plasma membrane TAS GO:0010008 endosome membrane TAS GO:0012506 vesicle membrane IEA GO:0030669 clathrin-coated endocytic vesicle membrane TAS GO:0031904 endosome lumen TAS GO:0031983 vesicle lumen IEA GO:0034359 mature chylomicron IDA GO:0034360 chylomicron remnant TAS GO:0034361 very-low-density lipoprotein particle IDA GO:0034362 low-density lipoprotein particle IDA GO:0034363 intermediate-density lipoprotein particle IDA GO:0042627 chylomicron IDA molecular_function GO:0005319 lipid transporter activity IEA GO:0005543 phospholipid binding IDA GO:0008201 heparin binding IDA GO:0017127 cholesterol transporter activity IMP GO:0019899 enzyme binding IPI GO:0046982 protein heterodimerization activity IPI GO:0050750 low-density lipoprotein particle receptor binding IMP

Protein-protein interaction details for APOB (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MTTP Two-hybrid physical 9915855 CANX Affinity Capture-Western physical 14498830 CALR Affinity Capture-Western physical 10513896 BGN Reconstituted Complex physical 12070165 HSP90B1 Affinity Capture-Western physical 12397072 PDIA4 Affinity Capture-Western physical 12397072 CALCR Affinity Capture-Western physical 12397072 PPIB Affinity Capture-Western physical 12397072 HSP90B1 Co-fractionation physical 12397072 PDIA4 Co-fractionation physical 12397072 CALCR Co-fractionation physical 12397072 PPIB Co-fractionation physical 12397072 HSP90B1 Affinity Capture-RNA physical 9694898 PDIA4 Affinity Capture-RNA physical 9694898 CALCR Affinity Capture-RNA physical 9694898 SEC61A1 Affinity Capture-Western physical 9565615 SEC61B Affinity Capture-Western physical 9565615 LIPC Reconstituted Complex physical 9685400 UBC Affinity Capture-Western physical 15618547 LRP6 Reconstituted Complex physical 18948618 CANX Affinity Capture-Western physical 9765244 UCHL5 Affinity Capture-MS physical 21800051 UBC Affinity Capture-Western physical 12670940