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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARF6 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001889 liver development IEA GO:0006184 GTP catabolic process TAS GO:0006915 apoptosis IEA GO:0006928 cellular component movement TAS GO:0007155 cell adhesion TAS GO:0007264 small GTPase mediated signal transduction IEA GO:0007399 nervous system development IEA GO:0015031 protein transport IEA GO:0016192 vesicle-mediated transport TAS GO:0030154 cell differentiation IEA GO:0030838 positive regulation of actin filament polymerization IMP GO:0030866 cortical actin cytoskeleton organization IMP GO:0031529 ruffle organization IDA GO:0034394 protein localization at cell surface ISS GO:0035020 regulation of Rac protein signal transduction IDA GO:0048261 negative regulation of receptor-mediated endocytosis TAS GO:0051489 regulation of filopodium assembly IDA GO:0060998 regulation of dendritic spine development ISS GO:0090004 positive regulation of establishment of protein localization in plasma membrane ISS cellular_component GO:0001726 ruffle IDA GO:0005622 intracellular IEA GO:0005624 membrane fraction TAS GO:0005737 cytoplasm IEA GO:0005768 endosome IDA GO:0005768 endosome TAS GO:0005769 early endosome IEA GO:0005794 Golgi apparatus IEA GO:0005886 plasma membrane IDA GO:0005938 cell cortex IDA GO:0010008 endosome membrane IEA GO:0031527 filopodium membrane IDA GO:0055037 recycling endosome IEA molecular_function GO:0000166 nucleotide binding IEA GO:0003924 GTPase activity TAS GO:0005515 protein binding IPI GO:0005525 GTP binding TAS GO:0031996 thioesterase binding IPI

Protein-protein interaction details for ARF6 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ARFIP2 Two-hybrid physical 9312003 LRPPRC Affinity Capture-MS physical 17353931 IQGAP1 Affinity Capture-MS physical 17353931 DYNC1H1 Affinity Capture-MS physical 17353931 KIAA0368 Affinity Capture-MS physical 17353931 YARS Affinity Capture-MS physical 17353931 EPPK1 Affinity Capture-MS physical 17353931 DHPS Affinity Capture-MS physical 17353931 PABPC4 Affinity Capture-MS physical 17353931 GART Affinity Capture-MS physical 17353931 EIF6 Affinity Capture-MS physical 17353931 EXOC5 Two-hybrid physical 14662749 EXOC5 Reconstituted Complex physical 14662749 EXOC5 Affinity Capture-Western physical 14662749 PIP5K1C Affinity Capture-Western physical 12847086 CHRM3 Affinity Capture-Western physical 12799371 CHRM3 Reconstituted Complex physical 12799371 AP3B1 Reconstituted Complex physical 11926829 AP3S2 Reconstituted Complex physical 11926829 ARRB1 Affinity Capture-Western physical 11533043 ARRB2 Affinity Capture-Western physical 11533043 ARRB1 Reconstituted Complex physical 11533043 CYTH2 Biochemical Activity physical 9417041 ARFIP2 Two-hybrid physical 11478794 ARFIP2 Reconstituted Complex physical 11478794 RALA Affinity Capture-Western physical 12509462 PLD1 Affinity Capture-Western physical 12379803 ARFIP2 Reconstituted Complex physical 9312003 MEPCE Affinity Capture-MS physical 17643375 RUVBL2 Affinity Capture-MS physical 17643375 EGFR PCA physical 20029029 UBC Affinity Capture-Western physical 18094045 FBXO8 Biochemical Activity physical 18094045 FBXO8 Co-localization physical 18094045 CYTH2 Affinity Capture-Western physical 18094045 ASAP1 Affinity Capture-Western physical 18094045 GGA3 Reconstituted Complex physical 20848231 UBC Reconstituted Complex physical 20848231