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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ARRB2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001932
regulation of protein phosphorylation
IEA
GO:0002031
G-protein coupled receptor internalization
IDA
GO:0002031
G-protein coupled receptor internalization
IMP
GO:0002032
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
IMP
GO:0006366
transcription from RNA polymerase II promoter
IDA
GO:0007179
transforming growth factor beta receptor signaling pathway
IDA
GO:0007596
blood coagulation
TAS
GO:0007628
adult walking behavior
IEA
GO:0008277
regulation of G-protein coupled receptor protein signaling pathway
IEA
GO:0015031
protein transport
IEA
GO:0016567
protein ubiquitination
IMP
GO:0030168
platelet activation
TAS
GO:0031397
negative regulation of protein ubiquitination
IDA
GO:0031623
receptor internalization
IDA
GO:0032088
negative regulation of NF-kappaB transcription factor activity
IDA
GO:0032226
positive regulation of synaptic transmission, dopaminergic
IEA
GO:0032691
negative regulation of interleukin-1 beta production
IEA
GO:0032695
negative regulation of interleukin-12 production
IEA
GO:0032715
negative regulation of interleukin-6 production
IEA
GO:0032720
negative regulation of tumor necrosis factor production
IEA
GO:0034122
negative regulation of toll-like receptor signaling pathway
IEA
GO:0043161
proteasomal ubiquitin-dependent protein catabolic process
IMP
GO:0045953
negative regulation of natural killer cell mediated cytotoxicity
IMP
GO:0051897
positive regulation of protein kinase B signaling cascade
IEA
GO:0060326
cell chemotaxis
IMP
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IDA
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IMP
cellular_component
GO:0005622
intracellular
IEA
GO:0005634
nucleus
IDA
GO:0005737
cytoplasm
IDA
GO:0005829
cytosol
TAS
GO:0005886
plasma membrane
IDA
GO:0005905
coated pit
IEA
GO:0016023
cytoplasmic membrane-bounded vesicle
IEA
GO:0031410
cytoplasmic vesicle
IDA
molecular_function
GO:0001664
G-protein-coupled receptor binding
IPI
GO:0005102
receptor binding
IPI
GO:0005515
protein binding
IPI
GO:0031625
ubiquitin protein ligase binding
IPI
GO:0031701
angiotensin receptor binding
IPI
GO:0043422
protein kinase B binding
IEA
Protein-protein interaction details for ARRB2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
RALGDS
Two-hybrid
physical
12105416
NOLC1
Affinity Capture-MS
physical
17353931
TCOF1
Affinity Capture-MS
physical
17353931
DDX27
Affinity Capture-MS
physical
17353931
AP3B1
Affinity Capture-MS
physical
17353931
KPNA3
Affinity Capture-MS
physical
17353931
KPNA4
Affinity Capture-MS
physical
17353931
BOP1
Affinity Capture-MS
physical
17353931
ARRB1
Affinity Capture-MS
physical
17353931
MRPL44
Affinity Capture-MS
physical
17353931
MRPL43
Affinity Capture-MS
physical
17353931
FBL
Affinity Capture-MS
physical
17353931
PES1
Affinity Capture-MS
physical
17353931
RPL7L1
Affinity Capture-MS
physical
17353931
RAB5C
Affinity Capture-MS
physical
17353931
SMARCC2
Two-hybrid
physical
16169070
MED8
Two-hybrid
physical
16169070
STC2
Two-hybrid
physical
16169070
MAPK10
Affinity Capture-Western
physical
11356842
RALGDS
Affinity Capture-Western
physical
12105416
RALGDS
Affinity Capture-Western
physical
12105416
ARF6
Affinity Capture-Western
physical
11533043
CYTH2
Affinity Capture-Western
physical
11533043
CYTH2
Reconstituted Complex
physical
11533043
OPRD1
Reconstituted Complex
physical
11259507
MDM2
Affinity Capture-Western
physical
12488444
MDM2
Affinity Capture-Western
physical
12488444
AVPR2
Affinity Capture-Western
physical
12473660
MAPK3
Affinity Capture-Western
physical
12473660
MDM2
Affinity Capture-Western
physical
12538596
LHCGR
Reconstituted Complex
physical
11867621
PTAFR
Affinity Capture-Western
physical
11729201
AP2B1
Two-hybrid
physical
10097102
AP2B1
Reconstituted Complex
physical
12070169
MAP3K5
Affinity Capture-Western
physical
11090355
MAP2K4
Affinity Capture-Western
physical
11090355
NEDD4
Affinity Capture-Western
physical
18544533
MDM2
Affinity Capture-Western
physical
18544533
ITCH
Affinity Capture-Western
physical
18544533
ITCH
Affinity Capture-Western
physical
17947233
ITCH
Reconstituted Complex
physical
17947233
CDC42
Two-hybrid
physical
20936779
UBC
FRET
physical
15782195
UBC
Affinity Capture-Western
physical
15782195
UBC
Affinity Capture-Western
physical
15699045
MAPK1
Affinity Capture-Western
physical
15699045
UBC
Affinity Capture-Western
physical
12574160
UBC
Affinity Capture-Western
physical
11588219
MDM2
Biochemical Activity
physical
11588219
DRD4
Affinity Capture-Western
physical
20100572
USP33
Affinity Capture-Western
physical
19424180
GPR56
Affinity Capture-Western
physical
21708946
USP33
Affinity Capture-Western
physical
19363159
UBC
Affinity Capture-Western
physical
19363159
USP33
Reconstituted Complex
physical
19363159
PARK2
Affinity Capture-Western
physical
21466165
PARK2
Affinity Capture-Western
physical
21466165
PARK2
Reconstituted Complex
physical
21466165
UBC
Affinity Capture-Western
physical
21466165
MDM2
Affinity Capture-Western
physical
21466165
IGF1R
Affinity Capture-Western
physical
19165858
MAP3K5
Affinity Capture-Western
physical
19306926
STUB1
Affinity Capture-Western
physical
19306926
TRAF3
Affinity Capture-Western
physical
11226259
MAP2K1
Affinity Capture-Western
physical
11226259
MAPK1
Affinity Capture-Western
physical
11226259
AGTR1
Affinity Capture-Western
physical
11226259
AKT1
Affinity Capture-Western
physical
18191226
AKT1
Reconstituted Complex
physical
18191226
MDM2
Co-localization
physical
21389118
MDM2
Affinity Capture-Western
physical
21389118
MDM2
Affinity Capture-Western
physical
21389118