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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ASCL1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001764neuron migrationIEA
GO:0003359noradrenergic neuron fate commitmentIMP
GO:0006351transcription, DNA-dependentIDA
GO:0007219Notch signaling pathwayIDA
GO:0007389pattern specification processIEA
GO:0007400neuroblast fate determinationIEA
GO:0007405neuroblast proliferationIEA
GO:0010226response to lithium ionIEA
GO:0014003oligodendrocyte developmentIEA
GO:0021527spinal cord association neuron differentiationIEA
GO:0021530spinal cord oligodendrocyte cell fate specificationIEA
GO:0021779oligodendrocyte cell fate commitmentIEA
GO:0021879forebrain neuron differentiationIEA
GO:0021892cerebral cortex GABAergic interneuron differentiationIEP
GO:0021954central nervous system neuron developmentIEA
GO:0021987cerebral cortex developmentIEA
GO:0022008neurogenesisIDA
GO:0032526response to retinoic acidIEP
GO:0043066negative regulation of apoptosisIMP
GO:0043525positive regulation of neuron apoptosisIEA
GO:0045665negative regulation of neuron differentiationIDA
GO:0045666positive regulation of neuron differentiationISS
GO:0045747positive regulation of Notch signaling pathwayIEA
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0048485sympathetic nervous system developmentNAS
GO:0048665neuron fate specificationIEA
GO:0050769positive regulation of neurogenesisIEA
GO:0051593response to folic acidIEA
GO:0060163subpallium neuron fate commitmentIEA
GO:0060165regulation of timing of subpallium neuron differentiationIEA
GO:0060166olfactory pit developmentIEA
GO:0060487lung epithelial cell differentiationNAS
GO:0061100lung neuroendocrine cell differentiationIEA
GO:0061102stomach neuroendocrine cell differentiationIEA
GO:0061103carotid body glomus cell differentiationIEA
GO:0061104adrenal chromaffin cell differentiationIEA
GO:0070849response to epidermal growth factor stimulusIEA
GO:0071259cellular response to magnetismIEA
cellular_component
GO:0005634nucleusIDA
GO:0043025neuronal cell bodyIEA
molecular_function
GO:0000989transcription factor binding transcription factor activityISS
GO:0003677DNA bindingISS
GO:0003690double-stranded DNA bindingIEA
GO:0003700sequence-specific DNA binding transcription factor activityIDA
GO:0005515protein bindingIPI
GO:0042803protein homodimerization activityIEA
GO:0043425bHLH transcription factor bindingIPI
GO:0043565sequence-specific DNA bindingIEA
GO:0070888E-box bindingIDA

Protein-protein interaction details for ASCL1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
EP300Affinity Capture-Westernphysical11564735
TCF4Reconstituted Complexphysical10903890
TCF4Two-hybridphysical10903890
MEF2AAffinity Capture-Westernphysical8662987
MEF2AReconstituted Complexphysical8662987