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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ATP1A1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002026regulation of the force of heart contractionIEA
GO:0002028regulation of sodium ion transportISS
GO:0006754ATP biosynthetic processIEA
GO:0006812cation transportIEA
GO:0006813potassium ion transportIEA
GO:0008217regulation of blood pressureIEA
GO:0031947negative regulation of glucocorticoid biosynthetic processIEA
GO:0034220ion transmembrane transportTAS
GO:0042493response to drugIEA
GO:0045822negative regulation of heart contractionIEA
GO:0045823positive regulation of heart contractionIEA
GO:0045989positive regulation of striated muscle contractionIEA
GO:0055085transmembrane transportTAS
cellular_component
GO:0005624membrane fractionTAS
GO:0005792microsomeIEA
GO:0005886plasma membraneIDA
GO:0005886plasma membraneTAS
GO:0005890sodium:potassium-exchanging ATPase complexTAS
GO:0016020membraneIEA
GO:0016021integral to membraneIEA
GO:0016021integral to membraneISS
GO:0016323basolateral plasma membraneIEA
GO:0042383sarcolemmaIEA
GO:0042470melanosomeIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:00038694-nitrophenylphosphatase activityIEA
GO:0005391sodium:potassium-exchanging ATPase activityIEA
GO:0005391sodium:potassium-exchanging ATPase activityISS
GO:0005391sodium:potassium-exchanging ATPase activityTAS
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0015077monovalent inorganic cation transmembrane transporter activityIEA
GO:0015662ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismIEA
GO:0016787hydrolase activityIEA
GO:0016820hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for ATP1A1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PRKCABiochemical Activityphysical15069082
MAPK1Biochemical Activityphysical15069082
MAPK3Biochemical Activityphysical15069082
FXYD1Affinity Capture-Westernphysical14597563
EZH2Two-hybridphysical16169070
HGSReconstituted Complexphysical19019082
UBCAffinity Capture-MSphysical16196087
HDAC5Affinity Capture-MSphysical21081666
UBCAffinity Capture-MSphysical18781797
UBCAffinity Capture-MSphysical21987572