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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for APTX (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000012 single strand break repair IDA GO:0006302 double-strand break repair IDA GO:0006974 response to DNA damage stimulus IMP GO:0008219 cell death IEA GO:0031647 regulation of protein stability IMP GO:0042542 response to hydrogen peroxide IDA cellular_component GO:0000785 chromatin IDA GO:0000790 nuclear chromatin IDA GO:0005622 intracellular IEA GO:0005634 nucleus IEA GO:0005654 nucleoplasm IDA GO:0005730 nucleolus IDA molecular_function GO:0003682 chromatin binding IDA GO:0003684 damaged DNA binding IDA GO:0003690 double-stranded DNA binding IDA GO:0003725 double-stranded RNA binding IDA GO:0003824 catalytic activity IEA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IEA GO:0008967 phosphoglycolate phosphatase activity IDA GO:0016787 hydrolase activity IEA GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity IDA GO:0046403 polynucleotide 3'-phosphatase activity IDA GO:0046872 metal ion binding IEA GO:0047485 protein N-terminus binding IPI GO:0051219 phosphoprotein binding IPI

Protein-protein interaction details for APTX (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID XRCC1 Affinity Capture-Western physical 15555565 XRCC1 Two-hybrid physical 15555565 XRCC1 Affinity Capture-Western physical 15555565 XRCC1 Two-hybrid physical 15555565 PARP1 Affinity Capture-Western physical 15555565 PARP1 Two-hybrid physical 15555565 TP53 Affinity Capture-Western physical 15044383 XRCC1 Affinity Capture-Western physical 15044383 PARP1 Affinity Capture-Western physical 15044383 PARP1 Affinity Capture-Western physical 15044383 XRCC1 Affinity Capture-Western physical 15044383 PARP1 Reconstituted Complex physical 15044383 TP53 Reconstituted Complex physical 15044383 XRCC1 Reconstituted Complex physical 15044383 BANF1 Affinity Capture-MS physical 19759913