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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ALS2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001701in utero embryonic developmentIEA
GO:0007032endosome organizationIGI
GO:0007032endosome organizationNAS
GO:0007409axonogenesisIEA
GO:0008219cell deathIEA
GO:0032855positive regulation of Rac GTPase activityIDA
GO:0035022positive regulation of Rac protein signal transductionIC
GO:0035023regulation of Rho protein signal transductionIEA
GO:0045860positive regulation of protein kinase activityIDA
GO:0048812neuron projection morphogenesisIDA
GO:0051036regulation of endosome sizeIEP
GO:0071902positive regulation of protein serine/threonine kinase activityIDA
cellular_component
GO:0001726ruffleISS
GO:0005622intracellularIEA
GO:0005737cytoplasmIEA
GO:0005769early endosomeIDA
GO:0005792microsomeIEA
GO:0005813centrosomeIDA
GO:0005829cytosolIDA
GO:0016020membraneIEA
GO:0019717synaptosomeIEA
GO:0030027lamellipodiumISS
GO:0030424axonIEA
GO:0030425dendriteIDA
GO:0030426growth coneISS
GO:0042598vesicular fractionIDA
GO:0043025neuronal cell bodyIEA
GO:0043234protein complexIDA
molecular_function
GO:0005085guanyl-nucleotide exchange factor activityIDA
GO:0005087Ran guanyl-nucleotide exchange factor activityNAS
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA
GO:0017112Rab guanyl-nucleotide exchange factor activityIDA
GO:0017137Rab GTPase bindingIDA
GO:0017137Rab GTPase bindingNAS
GO:0030676Rac guanyl-nucleotide exchange factor activityIDA
GO:0042803protein homodimerization activityIPI
GO:0043539protein serine/threonine kinase activator activityIDA

Protein-protein interaction details for ALS2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
YWHABAffinity Capture-MSphysical15324660