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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACTA1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006936 muscle contraction TAS GO:0009612 response to mechanical stimulus IEA GO:0009991 response to extracellular stimulus IEA GO:0010226 response to lithium ion IEA GO:0016049 cell growth IEA GO:0030049 muscle filament sliding TAS GO:0030240 skeletal muscle thin filament assembly IMP GO:0043503 skeletal muscle fiber adaptation IEA GO:0048545 response to steroid hormone stimulus IEA GO:0048741 skeletal muscle fiber development ISS cellular_component GO:0001725 stress fiber IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005856 cytoskeleton IEA GO:0005865 striated muscle thin filament IDA GO:0005884 actin filament IDA GO:0015629 actin cytoskeleton IMP GO:0030017 sarcomere IDA molecular_function GO:0000166 nucleotide binding IEA GO:0005200 structural constituent of cytoskeleton TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding TAS GO:0017022 myosin binding TAS GO:0043531 ADP binding TAS

Protein-protein interaction details for ACTA1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID APC2 Co-localization physical 11691822 DVL1L1 Affinity Capture-Western physical 12384700 ETV6 Co-localization physical 9695962 CDH2 Affinity Capture-Western physical 12438242 TRIP6 Co-localization physical 14688263 PHACTR1 Affinity Capture-Western physical 15107502 PPP1CA Affinity Capture-Western physical 15107502 MLPH Affinity Capture-Western physical 15059972 KLHL20 Reconstituted Complex physical 14668487 PFDN1 Reconstituted Complex physical 14634002 MARK4 Affinity Capture-MS physical 14594945 XPO6 Affinity Capture-MS physical 14592989 MIB2 Two-hybrid physical 14507647 MIB2 Reconstituted Complex physical 14507647 DNMBP Affinity Capture-MS physical 14506234 TNNI3K Two-hybrid physical 12721663 TES Affinity Capture-Western physical 12695497 GRB2 Affinity Capture-MS physical 12577067 CFL1 Affinity Capture-MS physical 11950878 TMSB4X Reconstituted Complex physical 11812134 CSNK1A1 Affinity Capture-MS physical 12062430 GSN Co-crystal Structure physical 10583954 TAGLN Co-fractionation physical 11053353 TSC1 Co-localization physical 10806479 RPS6KB1 Reconstituted Complex physical 15149849 NRAP Reconstituted Complex physical 10320340 PRKCE Affinity Capture-Western physical 11897493 PRKCE Affinity Capture-MS physical 11897493 GC Co-crystal Structure physical 12554937 CNN1 Reconstituted Complex physical 2161834 PPP1R9B Reconstituted Complex physical 12417592 SCIN Reconstituted Complex physical 12438125 TMSB4Y Reconstituted Complex physical 8416954 TMSB4X Reconstituted Complex physical 9153421 CCT4 Co-crystal Structure physical 11580270 PCYT1B Co-crystal Structure physical 11580270 CCT5 Co-crystal Structure physical 11580270 FSCN1 Reconstituted Complex physical 8999969 DMD Reconstituted Complex physical 1544421 VIM Affinity Capture-Western physical 11441066 SPTAN1 Affinity Capture-Western physical 11441066 COTL1 Reconstituted Complex physical 11297527 USP25 Two-hybrid physical 16501887 USP25 Reconstituted Complex physical 16501887 SMARCB1 Affinity Capture-Western physical 16568092 AKT1 Affinity Capture-Western physical 16568092 HDAC8 Affinity Capture-Western physical 15772115 DHX9 Co-purification physical 11687588 DHX9 Affinity Capture-Western physical 11687588 DHX9 Reconstituted Complex physical 11687588 HDAC1 Affinity Capture-MS physical 11102443 CTNNBL1 Affinity Capture-MS physical 21385873 HDAC4 Reconstituted Complex physical 21464227 MORF4L1 Affinity Capture-MS physical 17573780 MORF4L2 Affinity Capture-MS physical 17573780 C20orf20 Affinity Capture-MS physical 17573780 CFL1 Reconstituted Complex physical 21723825 CBL Affinity Capture-MS physical 21203488 DNASE1 Co-crystal Structure physical 2395459 POU5F1 Affinity Capture-RNA physical 21151833 DMAP1 Affinity Capture-MS physical 14966270 KAT5 Affinity Capture-MS physical 14966270 NCOA3 Affinity Capture-MS physical 16051665 EP300 Affinity Capture-MS physical 16051665 UBE3A Affinity Capture-MS physical 16051665 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572