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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ANAPC1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000278 mitotic cell cycle TAS GO:0007067 mitosis IEA GO:0007094 mitotic cell cycle spindle assembly checkpoint TAS GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0051301 cell division IEA GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0070979 protein K11-linked ubiquitination IDA cellular_component GO:0005634 nucleus IEA GO:0005654 nucleoplasm TAS GO:0005680 anaphase-promoting complex IDA GO:0005829 cytosol TAS molecular_function

Protein-protein interaction details for ANAPC1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ANAPC11 Reconstituted Complex physical 12956947 ANAPC2 Reconstituted Complex physical 12956947 FZR1 Reconstituted Complex physical 12956947 ANAPC4 Reconstituted Complex physical 12956947 ANAPC5 Reconstituted Complex physical 12956947 ANAPC7 Reconstituted Complex physical 12956947 APC2 Affinity Capture-Western physical 12956947 CDC27 Affinity Capture-Western physical 12956947 ANAPC4 Affinity Capture-Western physical 12956947 CDH1 Reconstituted Complex physical 12956947 CDC27 Co-purification physical 11076961 ANAPC4 Co-purification physical 11076961 ANAPC5 Co-purification physical 11076961 CDC16 Co-purification physical 11076961 CDC23 Co-purification physical 11076961 ANAPC2 Co-purification physical 11076961 ANAPC7 Co-purification physical 11076961 CDC20 Affinity Capture-Western physical 18997788 RPAP3 Affinity Capture-MS physical 17643375 RPAP1 Affinity Capture-MS physical 17643375 MDC1 Affinity Capture-MS physical 17827148 PTTG1 Biochemical Activity physical 20080579 CCNB1 Biochemical Activity physical 20080579 CDC16 Affinity Capture-MS physical 20360068 CDC27 Affinity Capture-MS physical 22193957 CCNB1 Biochemical Activity physical 22193957 PTTG1 Biochemical Activity physical 22193957 UBC Affinity Capture-MS physical 21987572