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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACTN1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002576 platelet degranulation TAS GO:0007596 blood coagulation TAS GO:0030168 platelet activation TAS GO:0034329 cell junction assembly TAS GO:0042981 regulation of apoptosis NAS GO:0048041 focal adhesion assembly IMP GO:0051017 actin filament bundle assembly IEA GO:0051271 negative regulation of cellular component movement IMP cellular_component GO:0001725 stress fiber IEA GO:0001726 ruffle IEA GO:0005576 extracellular region TAS GO:0005634 nucleus IEA GO:0005730 nucleolus IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA GO:0005916 fascia adherens IEA GO:0005925 focal adhesion IMP GO:0015629 actin cytoskeleton IDA GO:0030017 sarcomere IEA GO:0030018 Z disc IEA GO:0030864 cortical actin cytoskeleton IEA GO:0031093 platelet alpha granule lumen TAS GO:0031143 pseudopodium TAS molecular_function GO:0003779 actin binding IEA GO:0005178 integrin binding IDA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0017166 vinculin binding IPI GO:0019904 protein domain specific binding IEA GO:0051015 actin filament binding IEA

Protein-protein interaction details for ACTN1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID XRCC4 Two-hybrid physical 16189514 MAGEA11 Two-hybrid physical 16189514 MYOZ1 Two-hybrid physical 16189514 CDH1 Affinity Capture-Western physical 9535896 PHB Affinity Capture-Western physical 12628297 SSX2IP Affinity Capture-Western physical 12446711 SSX2IP Reconstituted Complex physical 12446711 ITGB1 Reconstituted Complex physical 2116421 PKN1 Affinity Capture-Western physical 11802708 PKN1 Affinity Capture-Western physical 11802708 COL17A1 Two-hybrid physical 11739652 COL17A1 Affinity Capture-Western physical 11739652 MYOT Affinity Capture-Western physical 12499399 TTN Reconstituted Complex physical 11305911 ZYX Reconstituted Complex physical 10224105 PDLIM1 Affinity Capture-Western physical 10753915 PDLIM1 Reconstituted Complex physical 10753915 ACTN1 Co-crystal Structure physical 11470434 PYGB Reconstituted Complex physical 12211109 ZYX Two-hybrid physical 11423549 ZYX Reconstituted Complex physical 11423549 PDLIM1 Two-hybrid physical 11110697 PDLIM1 Affinity Capture-Western physical 11110697 CDK5R1 Two-hybrid physical 12223541 CDK5R2 Two-hybrid physical 12223541 CDK5R1 Affinity Capture-Western physical 12223541 CDK5R1 Reconstituted Complex physical 12223541 CDK5R2 Reconstituted Complex physical 12223541 CTNNA1 Affinity Capture-Western physical 7790378 GIPC1 Reconstituted Complex physical 10198040 GIPC1 Affinity Capture-Western physical 10198040 APC Two-hybrid physical 20936779 CEBPA Affinity Capture-MS physical 17082780 TERF1 Affinity Capture-MS physical 20811636 TERF2 Affinity Capture-MS physical 20811636 TJP1 Affinity Capture-MS physical 16944923 KAT2B Two-hybrid physical 15604093 MED14 Two-hybrid physical 15604093 ATXN7 Two-hybrid physical 21078624 CACNA1A Two-hybrid physical 21078624 NR1H3 Two-hybrid physical 15604093 SUMO1 Reconstituted Complex physical 19596686 UBC Affinity Capture-MS physical 22178446