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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACTN2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002576 platelet degranulation TAS GO:0007155 cell adhesion TAS GO:0007268 synaptic transmission TAS GO:0007596 blood coagulation TAS GO:0030035 microspike assembly IDA GO:0030049 muscle filament sliding TAS GO:0030168 platelet activation TAS GO:0042981 regulation of apoptosis NAS GO:0048041 focal adhesion assembly IMP GO:0051289 protein homotetramerization IDA cellular_component GO:0005576 extracellular region TAS GO:0005730 nucleolus IDA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005856 cytoskeleton NAS GO:0005884 actin filament TAS GO:0005925 focal adhesion IMP GO:0015629 actin cytoskeleton IDA GO:0030017 sarcomere IEA GO:0030018 Z disc IDA GO:0030175 filopodium IDA GO:0030864 cortical actin cytoskeleton IEA GO:0031093 platelet alpha granule lumen TAS GO:0031143 pseudopodium TAS GO:0043197 dendritic spine TAS molecular_function GO:0003779 actin binding IEA GO:0005178 integrin binding TAS GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0008307 structural constituent of muscle TAS GO:0031432 titin binding IDA GO:0031432 titin binding IPI GO:0042802 identical protein binding IPI GO:0046983 protein dimerization activity IDA GO:0051370 ZASP binding IDA GO:0051374 FATZ 1 binding IDA GO:0070080 titin Z domain binding IPI

Protein-protein interaction details for ACTN2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MYPN Two-hybrid physical 11309420 KCNA5 Two-hybrid physical 12860415 DLG1 Affinity Capture-Western physical 12860415 DLG1 Affinity Capture-Western physical 12860415 DISC1 Affinity Capture-Western physical 12812986 ST7 Two-hybrid physical 12809483 KCNA5 Two-hybrid physical 10812072 KCNA5 Reconstituted Complex physical 10812072 KCNA5 Affinity Capture-Western physical 10812072 KCNA5 Affinity Capture-Western physical 10812072 GRIN2B Two-hybrid physical 9009191 GRIN2B Co-fractionation physical 9009191 ADAM12 Affinity Capture-Western physical 10788519 ADAM12 Reconstituted Complex physical 10788519 MYOZ1 Two-hybrid physical 10984498 MYOZ1 Reconstituted Complex physical 10984498 TNN Reconstituted Complex physical 9817758 MYPN Two-hybrid physical 11309420 PDLIM1 Two-hybrid physical 10861853 DLG4 Reconstituted Complex physical 12435606 LDB3 Affinity Capture-Western physical 10391924 ACTN3 Far Western physical 9675099 ACTN3 Far Western physical 9675099 ACTN3 Reconstituted Complex physical 9675099 ACTN3 Reconstituted Complex physical 9675099 ACTN3 Affinity Capture-Western physical 9675099 ACTN3 Affinity Capture-Western physical 9675099 DISC1 Two-hybrid physical 12812986 YWHAQ Affinity Capture-MS physical 20618440 NRIP1 Two-hybrid physical 15604093 KAT2B Two-hybrid physical 15604093 MED14 Two-hybrid physical 15604093 SNW1 Two-hybrid physical 15604093 ITGB3BP Two-hybrid physical 15604093 ATXN7 Two-hybrid physical 21078624 NR1I2 Two-hybrid physical 15604093 PSMA3 Affinity Capture-MS physical 22079093 KCNN2 Reconstituted Complex physical 19815520 UBC Affinity Capture-MS physical 22178446