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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARHGEF7 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006915 apoptosis TAS GO:0007165 signal transduction TAS GO:0007173 epidermal growth factor receptor signaling pathway TAS GO:0007264 small GTPase mediated signal transduction TAS GO:0007399 nervous system development IEA GO:0008624 induction of apoptosis by extracellular signals TAS GO:0035023 regulation of Rho protein signal transduction IEA GO:0035556 intracellular signal transduction IEA GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway TAS GO:0043065 positive regulation of apoptosis IMP GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051056 regulation of small GTPase mediated signal transduction TAS cellular_component GO:0005622 intracellular IEA GO:0005829 cytosol TAS molecular_function GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005515 protein binding IPI

Protein-protein interaction details for ARHGEF7 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SHANK2 Two-hybrid physical 12626503 SHANK1 Two-hybrid physical 12626503 CBL Two-hybrid physical 12935897 SHANK3 Two-hybrid physical 12626503 SHANK2 Reconstituted Complex physical 12626503 SHANK2 Affinity Capture-Western physical 12626503 SHANK1 Affinity Capture-Western physical 12626503 SHANK2 Affinity Capture-Western physical 12626503 SHANK3 Affinity Capture-Western physical 12626503 SHANK1 Reconstituted Complex physical 12626503 TUBB3 Two-hybrid physical 16169070 GIT1 Two-hybrid physical 12473661 GIT1 Affinity Capture-Western physical 12473661 GIT1 Affinity Capture-Western physical 10428811 PPM1E Reconstituted Complex physical 11864573 PPM1F Reconstituted Complex physical 11864573 PAK1 Affinity Capture-Western physical 11157752 PAK3 Two-hybrid physical 9726964 CBL Affinity Capture-Western physical 12935897 CBL Affinity Capture-Western physical 16407834 CBL Reconstituted Complex physical 16407834 CBL Affinity Capture-Western physical 16407834 PAK1 Affinity Capture-Western physical 16407834 PAK1 Two-hybrid physical 20936779 CBL Affinity Capture-Western physical 14505571 CDC42 Affinity Capture-Western physical 14505571 CDC42 Reconstituted Complex physical 14505571