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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACVR1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle IMP GO:0001569 patterning of blood vessels IEA GO:0001655 urogenital system development IEA GO:0001701 in utero embryonic development IEA GO:0001702 gastrulation with mouth forming second IEA GO:0001707 mesoderm formation IEA GO:0001755 neural crest cell migration IEA GO:0002526 acute inflammatory response IEA GO:0006468 protein phosphorylation IDA GO:0006468 protein phosphorylation IEA GO:0007179 transforming growth factor beta receptor signaling pathway IDA GO:0007179 transforming growth factor beta receptor signaling pathway IEA GO:0007281 germ cell development IEA GO:0007368 determination of left/right symmetry IEA GO:0007498 mesoderm development IEA GO:0007507 heart development IEA GO:0009790 embryo development IEA GO:0009968 negative regulation of signal transduction IMP GO:0030278 regulation of ossification IMP GO:0030501 positive regulation of bone mineralization IMP GO:0030509 BMP signaling pathway IDA GO:0032926 negative regulation of activin receptor signaling pathway IMP GO:0043066 negative regulation of apoptosis IMP GO:0045669 positive regulation of osteoblast differentiation IMP GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0048641 regulation of skeletal muscle tissue development IEA GO:0051145 smooth muscle cell differentiation IEA GO:0060037 pharyngeal system development IEA GO:0071385 cellular response to glucocorticoid stimulus IEA cellular_component GO:0005887 integral to plasma membrane IDA GO:0016020 membrane IEA GO:0045177 apical part of cell IEA GO:0048179 activin receptor complex IDA GO:0048179 activin receptor complex IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IDA GO:0004675 transmembrane receptor protein serine/threonine kinase activity RCA GO:0004702 receptor signaling protein serine/threonine kinase activity IEA GO:0004872 receptor activity IEA GO:0005025 transforming growth factor beta receptor activity, type I IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0016361 activin receptor activity, type I IDA GO:0016361 activin receptor activity, type I IEA GO:0042803 protein homodimerization activity IDA GO:0046332 SMAD binding IDA GO:0046332 SMAD binding IEA GO:0046872 metal ion binding IEA GO:0048184 follistatin binding NAS GO:0048185 activin binding IDA GO:0048185 activin binding IEA GO:0050431 transforming growth factor beta binding IDA GO:0050431 transforming growth factor beta binding IEA

Protein-protein interaction details for ACVR1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID FNTA Two-hybrid physical 8599089 BMPR2 Two-hybrid physical 7791754 BMPR2 Affinity Capture-Western physical 7791754 BMPR2 Two-hybrid physical 7791754 BMPR2 Affinity Capture-Western physical 7791754 GDF5 Affinity Capture-Western physical 8702914 ENG Affinity Capture-Western physical 9872992 BMP7 Reconstituted Complex physical 8006002 SMAD5 Affinity Capture-Western physical 10652350 SMAD1 Affinity Capture-Western physical 10652350 SMAD1 Affinity Capture-Western physical 9748228 SMAD5 Affinity Capture-Western physical 9748228 ACVR1B Affinity Capture-Western physical 8612709 BMPR2 Two-hybrid physical 7890683 TGFBR2 Two-hybrid physical 7890683 TSC22D1 Affinity Capture-Western physical 21791611