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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACVR1B (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000082 G1/S transition of mitotic cell cycle IDA GO:0001701 in utero embryonic development IEA GO:0001942 hair follicle development IEA GO:0006355 regulation of transcription, DNA-dependent IDA GO:0006468 protein phosphorylation IDA GO:0006917 induction of apoptosis IMP GO:0007165 signal transduction IDA GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway TAS GO:0007417 central nervous system development IEA GO:0009790 embryo development IEA GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IEA GO:0018107 peptidyl-threonine phosphorylation IDA GO:0018107 peptidyl-threonine phosphorylation IEA GO:0030308 negative regulation of cell growth IDA GO:0032924 activin receptor signaling pathway IDA GO:0032927 positive regulation of activin receptor signaling pathway IDA GO:0032927 positive regulation of activin receptor signaling pathway IMP GO:0045648 positive regulation of erythrocyte differentiation IDA GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0046545 development of primary female sexual characteristics IEA GO:0046777 protein autophosphorylation IDA cellular_component GO:0005887 integral to plasma membrane IDA GO:0009986 cell surface IDA GO:0016020 membrane IEA GO:0048179 activin receptor complex IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IDA GO:0004675 transmembrane receptor protein serine/threonine kinase activity NAS GO:0004702 receptor signaling protein serine/threonine kinase activity IEA GO:0004872 receptor activity IEA GO:0005024 transforming growth factor beta-activated receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0005524 ATP binding IEA GO:0016361 activin receptor activity, type I IDA GO:0016361 activin receptor activity, type I TAS GO:0016772 transferase activity, transferring phosphorus-containing groups IEA GO:0017002 activin-activated receptor activity IDA GO:0019838 growth factor binding IPI GO:0031625 ubiquitin protein ligase binding IPI GO:0046332 SMAD binding IDA GO:0046332 SMAD binding IEA GO:0046872 metal ion binding IEA GO:0048185 activin binding IDA GO:0048185 activin binding IEA

Protein-protein interaction details for ACVR1B (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BMPR2 Two-hybrid physical 7791754 ACVR2B Co-purification physical 8622651 INHBB Affinity Capture-Western physical 9202237 INHBA Affinity Capture-Western physical 9202237 SMAD7 Affinity Capture-Western physical 12023024 SMAD2 Affinity Capture-Western physical 9892009 SMAD3 Affinity Capture-Western physical 9892009 ACVR2A Affinity Capture-Western physical 9892009 ACVR2A Affinity Capture-Western physical 8612709 ACVR1 Affinity Capture-Western physical 8612709 ACVR2B Affinity Capture-Western physical 8612709 TDGF1 Reconstituted Complex physical 11909953 SNX2 Affinity Capture-Western physical 11279102 SNX1 Affinity Capture-Western physical 11279102 FKBP1A Affinity Capture-Western physical 16720724 SMAD7 Affinity Capture-Western physical 16720724 SMAD7 Affinity Capture-Western physical 16720724 SMURF1 Affinity Capture-Western physical 16720724 FKBP1A PCA physical 15908921 UBC Affinity Capture-Western physical 20596523 TSC22D1 Affinity Capture-Western physical 21791611