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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARHGEF1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0007266 Rho protein signal transduction TAS GO:0008283 cell proliferation TAS GO:0035023 regulation of Rho protein signal transduction IEA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0050770 regulation of axonogenesis TAS GO:0050771 negative regulation of axonogenesis TAS GO:0050772 positive regulation of axonogenesis TAS cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane TAS molecular_function GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005096 GTPase activator activity IEA GO:0005515 protein binding IPI

Protein-protein interaction details for ARHGEF1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ATR Protein-peptide physical 10608806 ARHGEF1 Affinity Capture-Western physical 14712228 GNA13 Reconstituted Complex physical 14634662 GNA12 Reconstituted Complex physical 14634662 GNA13 Affinity Capture-Western physical 14634662 GNA12 Affinity Capture-Western physical 14634662 PIK3CA Affinity Capture-Western physical 12754211 PIK3CA Affinity Capture-Western physical 12754211 CD44 Affinity Capture-Western physical 12748184 CD44 Affinity Capture-Western physical 12748184 RHOA Biochemical Activity physical 12748184 GNA13 Affinity Capture-Western physical 12681510 GNA13 Affinity Capture-Western physical 12681510 RAP1A Biochemical Activity physical 12581858 HRAS Biochemical Activity physical 12581858 GNA13 Affinity Capture-Western physical 9641916 GNA13 Affinity Capture-Western physical 9641916 TAF10 Affinity Capture-MS physical 17643375 MEPCE Affinity Capture-MS physical 17643375 SREBF2 Two-hybrid physical 20936779 CSNK1E Two-hybrid physical 21900206