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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ACVR2B (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001822 kidney development IEA GO:0006355 regulation of transcription, DNA-dependent IDA GO:0007165 signal transduction IDA GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway TAS GO:0007368 determination of left/right symmetry IEA GO:0007389 pattern specification process IEA GO:0007507 heart development IEA GO:0009749 response to glucose stimulus IEA GO:0009791 post-embryonic development IEA GO:0009952 anterior/posterior pattern specification IMP GO:0030073 insulin secretion IEA GO:0030324 lung development IEA GO:0030501 positive regulation of bone mineralization IMP GO:0030509 BMP signaling pathway IDA GO:0030509 BMP signaling pathway TAS GO:0031016 pancreas development IEA GO:0032147 activation of protein kinase activity IEA GO:0032927 positive regulation of activin receptor signaling pathway IDA GO:0035265 organ growth IEA GO:0042475 odontogenesis of dentine-containing tooth IEA GO:0045669 positive regulation of osteoblast differentiation IMP GO:0048617 embryonic foregut morphogenesis IEA GO:0048705 skeletal system morphogenesis IEA GO:0060021 palate development IEA cellular_component GO:0005737 cytoplasm IDA GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane TAS GO:0009986 cell surface IDA molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IMP GO:0004675 transmembrane receptor protein serine/threonine kinase activity TAS GO:0004702 receptor signaling protein serine/threonine kinase activity IEA GO:0004712 protein serine/threonine/tyrosine kinase activity IEA GO:0004872 receptor activity IEA GO:0005024 transforming growth factor beta-activated receptor activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016362 activin receptor activity, type II TAS GO:0019838 growth factor binding IPI GO:0046872 metal ion binding IEA GO:0048185 activin binding IEA GO:0048186 inhibin beta-A binding IEA GO:0048187 inhibin beta-B binding IEA

Protein-protein interaction details for ACVR2B (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID ACVR1B Co-purification physical 8622651 GDF5 Affinity Capture-Western physical 8702914 ENG Affinity Capture-Western physical 9872992 INHBB Affinity Capture-Western physical 9202237 INHBA Affinity Capture-Western physical 9202237 BMP6 Affinity Capture-Western physical 10504300 MSTN Affinity Capture-Western physical 11459935 BMP7 Affinity Capture-Western physical 9748228 ACVR1B Affinity Capture-Western physical 8612709 SYNJ2BP Reconstituted Complex physical 11882656 SYNJ2BP Two-hybrid physical 11882656 SNX6 Affinity Capture-Western physical 11279102 SNX2 Affinity Capture-Western physical 11279102 SNX1 Affinity Capture-Western physical 11279102