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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ACVRL1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001525
angiogenesis
IMP
GO:0001701
in utero embryonic development
IEA
GO:0001936
regulation of endothelial cell proliferation
TAS
GO:0001937
negative regulation of endothelial cell proliferation
IEA
GO:0001938
positive regulation of endothelial cell proliferation
IEA
GO:0001955
blood vessel maturation
TAS
GO:0002043
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
TAS
GO:0006275
regulation of DNA replication
TAS
GO:0006355
regulation of transcription, DNA-dependent
IMP
GO:0006468
protein phosphorylation
IDA
GO:0007162
negative regulation of cell adhesion
IMP
GO:0007165
signal transduction
IDA
GO:0007179
transforming growth factor beta receptor signaling pathway
IDA
GO:0008015
blood circulation
IMP
GO:0008217
regulation of blood pressure
IMP
GO:0008285
negative regulation of cell proliferation
IMP
GO:0010596
negative regulation of endothelial cell migration
IDA
GO:0030308
negative regulation of cell growth
IDA
GO:0030336
negative regulation of cell migration
IMP
GO:0030513
positive regulation of BMP signaling pathway
IDA
GO:0035313
wound healing, spreading of epidermal cells
IMP
GO:0043535
regulation of blood vessel endothelial cell migration
TAS
GO:0045602
negative regulation of endothelial cell differentiation
IEA
GO:0045603
positive regulation of endothelial cell differentiation
IEA
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0051291
protein heterooligomerization
IEA
GO:0051895
negative regulation of focal adhesion assembly
IMP
cellular_component
GO:0005887
integral to plasma membrane
IDA
GO:0009986
cell surface
IDA
GO:0016020
membrane
IEA
GO:0030425
dendrite
IEA
GO:0043025
neuronal cell body
IEA
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0004672
protein kinase activity
IEA
GO:0004674
protein serine/threonine kinase activity
IDA
GO:0004674
protein serine/threonine kinase activity
IEA
GO:0004675
transmembrane receptor protein serine/threonine kinase activity
RCA
GO:0004702
receptor signaling protein serine/threonine kinase activity
IEA
GO:0004872
receptor activity
IEA
GO:0005024
transforming growth factor beta-activated receptor activity
IDA
GO:0005024
transforming growth factor beta-activated receptor activity
IEA
GO:0005025
transforming growth factor beta receptor activity, type I
IDA
GO:0005515
protein binding
IPI
GO:0005524
ATP binding
IDA
GO:0005524
ATP binding
IEA
GO:0016361
activin receptor activity, type I
IDA
GO:0016361
activin receptor activity, type I
TAS
GO:0016772
transferase activity, transferring phosphorus-containing groups
IEA
GO:0046332
SMAD binding
IDA
GO:0046872
metal ion binding
IEA
GO:0048185
activin binding
IDA
GO:0050431
transforming growth factor beta binding
IPI
Protein-protein interaction details for ACVRL1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
TGFB1
Affinity Capture-Western
physical
10716993
SNX6
Affinity Capture-Western
physical
11279102
TSC22D1
Affinity Capture-Western
physical
21791611