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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARHGEF6 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006915apoptosisNAS
GO:0006915apoptosisTAS
GO:0007254JNK cascadeNAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0008624induction of apoptosis by extracellular signalsTAS
GO:0034329cell junction assemblyTAS
GO:0035023regulation of Rho protein signal transductionIEA
GO:0043547positive regulation of GTPase activityNAS
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0051056regulation of small GTPase mediated signal transductionTAS
cellular_component
GO:0005622intracellularIC
GO:0005622intracellularIEA
GO:0005737cytoplasmIDA
GO:0005829cytosolTAS
molecular_function
GO:0005085guanyl-nucleotide exchange factor activityIEA
GO:0005089Rho guanyl-nucleotide exchange factor activityIEA
GO:0005089Rho guanyl-nucleotide exchange factor activityNAS
GO:0005096GTPase activator activityNAS
GO:0005515protein bindingIPI

Protein-protein interaction details for ARHGEF6 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PKLRAffinity Capture-Westernphysical12006652
GIT1Affinity Capture-Westernphysical10428811
ZNF580Two-hybridphysical21900206
PAK1Two-hybridphysical21900206
GIT1Two-hybridphysical21900206
GPRASP2Two-hybridphysical21900206
SH3GL3Two-hybridphysical21900206
TMEM108Two-hybridphysical21900206
UBCAffinity Capture-MSphysical22118674