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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for ARHGEF6 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006915
apoptosis
NAS
GO:0006915
apoptosis
TAS
GO:0007254
JNK cascade
NAS
GO:0007264
small GTPase mediated signal transduction
TAS
GO:0008624
induction of apoptosis by extracellular signals
TAS
GO:0034329
cell junction assembly
TAS
GO:0035023
regulation of Rho protein signal transduction
IEA
GO:0043547
positive regulation of GTPase activity
NAS
GO:0048011
nerve growth factor receptor signaling pathway
TAS
GO:0051056
regulation of small GTPase mediated signal transduction
TAS
cellular_component
GO:0005622
intracellular
IC
GO:0005622
intracellular
IEA
GO:0005737
cytoplasm
IDA
GO:0005829
cytosol
TAS
molecular_function
GO:0005085
guanyl-nucleotide exchange factor activity
IEA
GO:0005089
Rho guanyl-nucleotide exchange factor activity
IEA
GO:0005089
Rho guanyl-nucleotide exchange factor activity
NAS
GO:0005096
GTPase activator activity
NAS
GO:0005515
protein binding
IPI
Protein-protein interaction details for ARHGEF6 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
PKLR
Affinity Capture-Western
physical
12006652
GIT1
Affinity Capture-Western
physical
10428811
ZNF580
Two-hybrid
physical
21900206
PAK1
Two-hybrid
physical
21900206
GIT1
Two-hybrid
physical
21900206
GPRASP2
Two-hybrid
physical
21900206
SH3GL3
Two-hybrid
physical
21900206
TMEM108
Two-hybrid
physical
21900206
UBC
Affinity Capture-MS
physical
22118674