Gene information for SAP18 (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 10284 |
Official gene symbol | SAP18 |
Full name | Sin3A-associated protein, 18kDa |
Aliases | ,2HOR0202,MGC27131,SAP18P, |
Gene summary | Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq] |
Location | Chromosome: 13 Locus: |
Gene position | 21714653 - 21723224 Map Viewer |
OMIM ID | 602949 |