Gene information for BAIAP2 (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 10458 |
Official gene symbol | BAIAP2 |
Full name | BAI1-associated protein 2 |
Aliases | ,BAP2,FLAF3,IRSP53, |
Gene summary | The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Location | Chromosome: 17 Locus: |
Gene position | 79008947 - 79091232 Map Viewer |
OMIM ID | 605475 |