Gene information for ADAMTS8 (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 11095 |
Official gene symbol | ADAMTS8 |
Full name | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
Aliases | ,ADAM-TS8,FLJ41712,METH2, |
Gene summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq] |
Location | Chromosome: 11 Locus: |
Gene position | 130298539 - 130274818 Map Viewer |
OMIM ID | 605175 |