Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for CHKB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1120
Official gene symbolCHKB
Full namecholine kinase beta
Gene summaryCholine kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq]
LocationChromosome: 22   Locus: 
Gene position51021428 - 51017387  Map Viewer
OMIM ID612395