Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for SEC63 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID11231
Official gene symbolSEC63
Full nameSEC63 homolog (S. cerevisiae)
Gene summaryThe Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq]
LocationChromosome: 6   Locus: 
Gene position108279482 - 108188960  Map Viewer
OMIM ID608648