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| Entrez gene ID | 117145 |
| Official gene symbol | THEM4 |
| Full name | thioesterase superfamily member 4 |
| Aliases | ,CTMP,MGC29636, |
| Gene summary | Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq] |
| Location | Chromosome: 1 Locus: |
| Gene position | 151882113 - 151846060 Map Viewer |
| OMIM ID | 606388 |