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Entrez gene ID | 1363 |
Official gene symbol | CPE |
Full name | carboxypeptidase E |
Aliases | ,-, |
Gene summary | This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq] |
Location | Chromosome: 4 Locus: |
Gene position | 166300097 - 166419482 Map Viewer |