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| Entrez gene ID | 144568 |
| Official gene symbol | A2ML1 |
| Full name | alpha-2-macroglobulin-like 1 |
| Aliases | ,CPAMD9,DKFZp686C1729,DKFZp686D2011,DKFZp686G1812,DKFZp686L1821,DKFZp686O1010,FLJ16045,FLJ25179,FLJ39129,FLJ41597,FLJ41598,FLJ41607, |
| Gene summary | The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM] |
| Location | Chromosome: 12 Locus: |
| Gene position | 8975150 - 9029379 Map Viewer |
| OMIM ID | 610627 |