Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for A2ML1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID144568
Official gene symbolA2ML1
Full namealpha-2-macroglobulin-like 1
Gene summaryThe alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM]
LocationChromosome: 12   Locus: 
Gene position8975150 - 9029379  Map Viewer
OMIM ID610627