Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for CYBB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID1536
Official gene symbolCYBB
Full namecytochrome b-245, beta polypeptide
Gene summaryCytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq]
LocationChromosome: X   Locus: 
Gene position37639270 - 37672714  Map Viewer
OMIM ID300481