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Entrez gene ID | 1719 |
Official gene symbol | DHFR |
Full name | dihydrofolate reductase |
Aliases | ,DHFRP1,DYR, |
Gene summary | Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq] |
Location | Chromosome: 5 Locus: |
Gene position | 79950800 - 79922045 Map Viewer |
OMIM ID | 126060 |