Gene information for A2M (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 2 |
Official gene symbol | A2M |
Full name | alpha-2-macroglobulin |
Aliases | ,CPAMD5,DKFZp779B086,FWP007,S863-7, |
Gene summary | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq] |
Location | Chromosome: 12 Locus: |
Gene position | 9268558 - 9220304 Map Viewer |
OMIM ID | 103950 |