Gene information for F5 (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 2153 |
Official gene symbol | F5 |
Full name | coagulation factor V (proaccelerin, labile factor) |
Aliases | ,FVL,PCCF, |
Gene summary | This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq] |
Location | Chromosome: 1 Locus: |
Gene position | 169555769 - 169481192 Map Viewer |
OMIM ID | 612309 |