Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for F9 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2158
Official gene symbolF9
Full namecoagulation factor IX
Gene summaryThis gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq]
LocationChromosome: X   Locus: 
Gene position138612895 - 138645617  Map Viewer
OMIM ID300746