Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for RFX6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID222546
Official gene symbolRFX6
Full nameregulatory factor X, 6
Gene summaryThe nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.
LocationChromosome: 6   Locus: 
Gene position117198376 - 117253314  Map Viewer
OMIM ID612659