Gene information for LMTK2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
| Entrez gene ID | 22853 |
| Official gene symbol | LMTK2 |
| Full name | lemur tyrosine kinase 2 |
| Aliases | ,AATYK2,BREK,FLJ46659,KIAA1079,KPI-2,KPI2,LMR2,cprk, |
| Gene summary | The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq] |
| Location | Chromosome: 7 Locus: |
| Gene position | 97736197 - 97838945 Map Viewer |
| OMIM ID | 610989 |
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