Gene Protein Transcript Blast result Transcript specific probe-cluster
Gene information for GLCE (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID26035
Official gene symbolGLCE
Full nameglucuronic acid epimerase
Gene summaryHeparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM]
LocationChromosome: 15   Locus: 
Gene position69452973 - 69564544  Map Viewer
OMIM ID612134