Gene information for GLCE (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 26035 |
Official gene symbol | GLCE |
Full name | glucuronic acid epimerase |
Aliases | ,HSEPI,KIAA0836, |
Gene summary | Heparan sulfate (HS) is a negatively charged cell surface polysaccharide required for the biologic activities of circulating extracellular ligands. GLCE is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of HS, which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).[supplied by OMIM] |
Location | Chromosome: 15 Locus: |
Gene position | 69452973 - 69564544 Map Viewer |
OMIM ID | 612134 |