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Entrez gene ID | 26574 |
Official gene symbol | AATF |
Full name | apoptosis antagonizing transcription factor |
Aliases | ,CHE-1,CHE1,DED, |
Gene summary | The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq] |
Location | Chromosome: 17 Locus: |
Gene position | 35306175 - 35414171 Map Viewer |
OMIM ID | 608463 |