Gene information for PABPC1 (Homo sapiens)
(Information is obtained from NCBI Gene database) |
Entrez gene ID | 26986 |
Official gene symbol | PABPC1 |
Full name | poly(A) binding protein, cytoplasmic 1 |
Aliases | ,PAB1,PABP,PABP1,PABPC2,PABPL1, |
Gene summary | This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes. |
Location | Chromosome: 8 Locus: |
Gene position | 101734315 - 101715144 Map Viewer |
OMIM ID | 604679 |